Gene: PRDX5
Official Full Name: peroxiredoxin 5provided by HGNC
Gene Summary: This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein interacts with peroxisome receptor 1 and plays an antioxidant protective role in different tissues under normal conditions and during inflammatory processes. The use of alternate transcription start sites is thought to result in transcript variants that use different in-frame translational start codons to generate isoforms that are targeted to the mitochondrion (isoform L) or peroxisome/cytoplasm (isoform S). Multiple related pseudogenes have been defined for this gene. [provided by RefSeq, Nov 2017]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
GP00541 | PRDX5 gRNA1-gRNA2 KO plasmid | PRDX5 | $850 | |||
KO00788 | PRDX5 Knockout cell line(22Rv1) | Human | PRDX5 | 1:2~1:3 | Negative | Online Inquiry |
KO14895 | PRDX5 Knockout cell line (HeLa) | Human | PRDX5 | 1:3~1:6 | Negative | Online Inquiry |
KO14896 | PRDX5 Knockout cell line (HCT 116) | Human | PRDX5 | 1:2~1:4 | Negative | Online Inquiry |
KO14897 | PRDX5 Knockout cell line (HEK293) | Human | PRDX5 | 1:3~1:6 | Negative | Online Inquiry |
KO14898 | PRDX5 Knockout cell line (A549) | Human | PRDX5 | 1:3~1:4 | Negative | Online Inquiry |
PRDX5 Gene Knockout Cell Lines are genetically engineered cell models that have been designed to lack the expression of the peroxiredoxin 5 (PRDX5) gene. PRDX5 encodes a member of the peroxiredoxin family, which plays a crucial role in regulating oxidative stress within cells by maintaining cellular redox balance and detoxifying reactive oxygen species. The targeted knockout of PRDX5 facilitates the investigation of its functions in various biological processes, including cell proliferation, apoptosis, and responses to oxidative stress.
These knockout cell lines function by providing researchers with a controlled environment to study the specific phenotypic changes and molecular pathways associated with the absence of PRDX5. This can lead to insights into the gene's role in diseases such as cancer, neurodegeneration, and cardiovascular conditions, where oxidative stress is a significant factor. In clinical settings, the PRDX5 knockout cell lines serve as critical tools for drug discovery and development, helping to screen compounds that may modulate oxidative stress responses.
What sets PRDX5 Gene Knockout Cell Lines apart from other cell models is their specificity and reliability. Researchers can depend on these cells to yield reproducible results that directly reflect the biological consequences of PRDX5 deficiency. Unlike traditional cell lines that may exhibit variable expression of genes, these knockout lines ensure that the effects observed are due solely to the targeted deletion.
Moreover, the availability of these specialized cell lines supports the growing demand for model systems that accurately simulate disease states, providing a valuable platform for both foundational research and therapeutic development. Ultimately, the PRDX5 Gene Knockout Cell Lines represent a robust resource for those aiming to deepen their understanding of oxidative stress-related biology.
With our commitment to advancing research tools, our company brings extensive expertise in genetic engineering and cell line development, ensuring that researchers have access to high-quality models essential for their studies.
Please note that all services are for research use only. Not intended for any clinical use.
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