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PRDM13 Knockout Cell Lines

Gene: PRDM13

Official Full Name: PR/SET domain 13provided by HGNC

Gene Summary: Predicted to enable histone methyltransferase activity. Predicted to be involved in regulation of gene expression. Predicted to act upstream of or within negative regulation of transcription by RNA polymerase II and neurogenesis. Predicted to be active in nucleus. Implicated in pontocerebellar hypoplasia. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14899 PRDM13 Knockout cell line (HEK293) Human PRDM13 1:3~1:6 Negative Online Inquiry

Background

PRDM13 Gene Knockout Cell Lines are specially developed cellular models that have undergone targeted gene editing to disrupt the expression of the PRDM13 gene. This gene is known for its critical roles in various biological processes including development, differentiation, and cellular signaling. By creating knockout models, researchers can effectively evaluate the functional implications of gene loss, allowing for deeper insights into the molecular pathways influenced by PRDM13.

These cell lines utilize CRISPR/Cas9 genome editing technology, which provides a precise and efficient means of knocking out specific genes. The lack of PRDM13 expression leads to observable phenotypic changes, contributing to investigations in areas such as stem cell biology and cancer research. The ability to observe these alterations enables scientists to unravel complex signaling networks and appreciate the contribution of PRDM13 in cellular contexts.

The scientific importance of PRDM13 Gene Knockout Cell Lines extends to their applications in both research and clinical settings. They offer a powerful tool for characterizing gene function, identifying potential biomarkers, and testing therapeutic strategies in various diseases. Furthermore, these cell lines can serve as invaluable platforms for drug screening, enabling researchers to discover novel compounds that may target PRDM13-related pathways.

Compared to alternative approaches, such as transient transfection or RNA interference, the PRDM13 Gene Knockout Cell Lines provide a stable and reproducible model that ensures consistent expression profiles over time. This stability is crucial for longitudinal studies and facilitates the validation of findings across different experimental conditions.

For researchers and clinicians looking to deepen their understanding of genomic regulation and its implications in disease, these knockout cell lines present an exceptional opportunity. The value lies in their potential to transform basic discoveries into clinically relevant applications that could eventually lead to innovative therapies.

With extensive experience in developing genetic models and a commitment to advancing biological research, our company proudly offers PRDM13 Gene Knockout Cell Lines as part of our comprehensive portfolio of high-quality biological products tailored to meet the evolving needs of the scientific community.

Please note that all services are for research use only. Not intended for any clinical use.

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