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PPP5C Knockout Cell Lines

Gene: PPP5C

Official Full Name: protein phosphatase 5 catalytic subunitprovided by HGNC

Gene Summary: This gene encodes a serine/threonine phosphatase which is a member of the protein phosphatase catalytic subunit family. Proteins in this family participate in pathways regulated by reversible phosphorylation at serine and threonine residues; many of these pathways are involved in the regulation of cell growth and differentiation. The product of this gene has been shown to participate in signaling pathways in response to hormones or cellular stress, and elevated levels of this protein may be associated with breast cancer development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00185 PPP5C Knockout cell line (HEK293) Human PPP5C 1:3~1:6 Negative Online Inquiry
KO10538 PPP5C Knockout cell line (HeLa) Human PPP5C 1:3~1:6 Negative Online Inquiry
KO10539 PPP5C Knockout cell line (HCT 116) Human PPP5C 1:2~1:4 Negative Online Inquiry
KO10540 PPP5C Knockout cell line (A549) Human PPP5C 1:3~1:4 Negative Online Inquiry

Background

PPP5C Gene Knockout Cell Lines are engineered cellular models that have undergone precise genetic modifications to disrupt the expression of the PPP5C gene. This gene encodes a serine/threonine protein phosphatase involved in a multitude of signaling pathways, playing a crucial role in cellular processes such as cell growth, apoptosis, and DNA repair. By eliminating PPP5C, these knockout cell lines provide invaluable insights into the gene’s function and its impact on cellular behavior.

The key function of the PPP5C Gene Knockout Cell Lines is to facilitate the study of specific physiological effects resulting from the absence of PPP5C expression. Researchers can observe alterations in cell signaling, proliferation rates, and response to various stressors, effectively elucidating the role of this phosphatase in health and disease. The knockout model mimics pathological conditions, making it an essential tool for investigating the mechanisms behind cancers and other disorders linked to aberrant phosphatase activity.

The scientific importance of these cell lines is underscored by their application in both basic research and therapeutic development. They offer a robust system for drug screening, particularly to identify pharmacological agents that may modulate the activity of PPP5C-dependent pathways. This is particularly relevant given the increasing focus on targeted therapies in precision medicine.

What sets our PPP5C Gene Knockout Cell Lines apart from alternatives is the comprehensive validation process they undergo to ensure reliable results, coupled with advanced knockout techniques that minimize off-target effects. Our proprietary cell line configurations guarantee high levels of reproducibility, which is critical for obtaining rigorously interpretable data.

For researchers and clinicians, utilizing our PPP5C Gene Knockout Cell Lines provides a strategic advantage by allowing them to dissect the intricate functionalities of this gene in a controlled environment, ultimately driving innovation in research and development.

Our company has extensive expertise in creating and optimizing genetically modified cell lines, ensuring that our products meet the highest scientific standards. We are committed to supporting the research community with the tools they need to accelerate discoveries and translate findings into clinical applications.

Please note that all services are for research use only. Not intended for any clinical use.

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