Gene: PPP1R1C
Official Full Name: protein phosphatase 1 regulatory inhibitor subunit 1Cprovided by HGNC
Gene Summary: Protein phosphatase-1 (PP1) is a major serine/threonine phosphatase that regulates a variety of cellular functions. PP1 consists of a catalytic subunit (see PPP1CA; MIM 176875) and regulatory subunits that determine the subcellular localization of PP1 or regulate its function. PPP1R1C belongs to a group of PP1 inhibitory subunits that are themselves regulated by phosphorylation (Wang et al., 2008 [PubMed 18310074]).[supplied by OMIM, Feb 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO21990 | PPP1R1C Knockout cell line (HeLa) | Human | PPP1R1C | 1:3~1:6 | Negative | Online Inquiry |
KO21991 | PPP1R1C Knockout cell line (HCT 116) | Human | PPP1R1C | 1:2~1:4 | Negative | Online Inquiry |
KO21992 | PPP1R1C Knockout cell line (A549) | Human | PPP1R1C | 1:3~1:4 | Negative | Online Inquiry |
PPP1R1C Gene Knockout Cell Lines are genetically modified cell lines designed to facilitate the study of the PPP1R1C gene, which encodes the protein phosphatase 1 regulatory subunit 1C. This product serves as a crucial tool for researchers investigating the role of PPP1R1C in various cellular processes, including signal transduction, cell division, and modulation of protein phosphorylation dynamics. By knocking out this specific gene, researchers can elucidate its functional roles in healthy and pathological states, offering insights into diseases such as cancer, neurodegenerative disorders, and metabolic syndromes.
The primary mechanism of action involves the strategic inactivation of the PPP1R1C gene using CRISPR-Cas9 technology or similar gene-editing approaches. This targeted knockout allows for the observation of phenotypic alterations, gene expression changes, and behavioral shifts in signaling pathways that are otherwise regulated by PPP1R1C. The absence of this protein dynamically alters cellular homeostasis and can reveal compensatory mechanisms employed by the cell, further enriching our understanding of cellular biology.
From a scientific standpoint, the development and application of PPP1R1C Gene Knockout Cell Lines represent significant advancements in molecular biology and genetics. Their importance extends to biomedical research, where they can serve as model systems to explore the therapeutic potential of molecular interventions, enabling clinicians to develop targeted therapies that could correct aberrant signaling pathways associated with disease.
This product offers several compelling advantages over alternatives, including its specificity and efficiency in generating consistencies across experiments. By utilizing established knockout technology, researchers can expect reproducible results, enhancing the reliability of their findings. Additionally, PPP1R1C Gene Knockout Cell Lines are readily adaptable to high-throughput screening processes, making them invaluable for pharmaceutical research and drug discovery initiatives.
In a landscape where precision and reproducibility are paramount, the PPP1R1C Gene Knockout Cell Lines stand out as a must-have resource for researchers and clinicians alike. As a leader in the field of biological products, our company is committed to delivering high-quality, innovative solutions that empower the scientific community and advance research frontiers.
Please note that all services are for research use only. Not intended for any clinical use.
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