Gene: POU3F3
Official Full Name: POU class 3 homeobox 3provided by HGNC
Gene Summary: This gene encodes a POU-domain containing protein that functions as a transcription factor. The encoded protein recognizes an octamer sequence in the DNA of target genes. This protein may play a role in development of the nervous system. [provided by RefSeq, Apr 2015]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO05690 | POU3F3 Knockout cell line (HEK293) | Human | POU3F3 | 1:3~1:6 | Negative | Online Inquiry |
POU3F3 Gene Knockout Cell Lines are engineered cellular models that have been systematically modified to disrupt the expression of the POU3F3 gene, a key transcription factor implicated in various neural developmental processes. These cell lines serve as powerful tools for understanding the functional implications of POU3F3 in both health and disease contexts, particularly in neurodevelopmental and neurodegenerative disorders.
The mechanism by which these knockout cell lines operate involves the use of advanced gene-editing techniques, such as CRISPR-Cas9 technology, allowing for precise deletions or insertions that effectively abolish POU3F3 gene expression. This targeted approach enables researchers to dissect the biological pathways regulated by POU3F3, thereby elucidating its role in gene regulation, cellular differentiation, and response to environmental stimuli.
In scientific research and clinical settings, POU3F3 Gene Knockout Cell Lines are invaluable for investigating the molecular underpinnings of disorders such as schizophrenia, autism spectrum disorders, and other cognitive dysfunctions. Their application extends to drug discovery, where researchers can screen for compounds that may modulate the pathways influenced by POU3F3, paving the way for novel therapeutic strategies.
What distinguishes our POU3F3 Gene Knockout Cell Lines from alternatives is the specificity and consistency of the knockout efficiency, ensuring reproducible results across experiments. Additionally, they come with comprehensive support and validation data, enhancing confidence in experimental design and data interpretation.
Researchers and clinicians value these cell lines for their potential to accelerate discoveries that could lead to transformative treatments. With our expertise in developing cutting-edge biological products, we are committed to providing high-quality tools that empower scientists to advance their work in molecular biology and related fields, ultimately contributing to the understanding and treatment of complex diseases.
Please note that all services are for research use only. Not intended for any clinical use.
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