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PLXDC2 Knockout Cell Lines

Gene: PLXDC2

Official Full Name: plexin domain containing 2provided by HGNC

Gene Summary: Predicted to be located in membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24530 PLXDC2 Knockout cell line (HeLa) Human PLXDC2 1:3~1:6 Negative Online Inquiry
KO24531 PLXDC2 Knockout cell line (HEK293) Human PLXDC2 1:3~1:6 Negative Online Inquiry

Background

PLXDC2 Gene Knockout Cell Lines are advanced biological models designed to facilitate comprehensive studies of the PLXDC2 gene, its function, and its implications in various physiological processes and diseases. By utilizing CRISPR/Cas9 genome-editing technology, these cell lines effectively disrupt the PLXDC2 gene, allowing researchers to observe the resulting phenotypic changes and elucidate the gene's role in cellular signaling pathways, inflammation, and tumorigenesis.

The primary function of these knockout cell lines is to provide a stable cellular system in which the effects of the loss of PLXDC2 can be studied in detail. This model allows for the examination of cellular behavior, such as proliferation, apoptosis, and differentiation, under controlled conditions, granting researchers insights into the gene's contributions to normal and pathological states. Mechanistically, the absence of PLXDC2 can influence several downstream signaling cascades that are integral to immune responses and oncogenic pathways, making these cell lines valuable for basic research and therapeutic development.

In a clinical or research setting, the PLXDC2 Gene Knockout Cell Lines serve as a critical tool for understanding diseases where PLXDC2 is implicated, such as certain cancers and autoimmune disorders. By enabling the exploration of gene-specific effects in vivo, these cell lines can aid in the development of targeted therapies, thus translating basic science into clinical applications.

One of the standout advantages of the PLXDC2 Gene Knockout Cell Lines is their accessibility and ease of use compared to other models. Researchers can interpret results in a straightforward context, reducing variability often associated with animal models. Moreover, they represent a cost-effective solution for high-throughput screening assays and drug discovery initiatives, enabling researchers to accelerate their projects without sacrificing data integrity or reproducibility.

For researchers and clinicians seeking to deepen their understanding of the PLXDC2 gene's functional biology, these knockout cell lines offer an unmatched resource that harnesses cutting-edge gene editing technology. Our company's commitment to providing high-quality research tools is backed by both extensive expertise in molecular biology and a rigorous quality assurance process, ensuring that our customers receive reliable and effective products that enhance scientific discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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