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PI4K2B Knockout Cell Lines

Gene: PI4K2B

Official Full Name: phosphatidylinositol 4-kinase type 2 betaprovided by HGNC

Gene Summary: This gene encodes a member of the type II PI4 kinase protein family. The encoded protein is primarily cytosolic and contributes to overall PI4-kinase activity along with other protein family members. This protein is involved in early T cell activation. [provided by RefSeq, Dec 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO07935 PI4K2B Knockout cell line (HeLa) Human PI4K2B 1:3~1:6 Negative Online Inquiry
KO07936 PI4K2B Knockout cell line (HCT 116) Human PI4K2B 1:2~1:4 Negative Online Inquiry
KO07937 PI4K2B Knockout cell line (HEK293) Human PI4K2B 1:3~1:6 Negative Online Inquiry
KO07938 PI4K2B Knockout cell line (A549) Human PI4K2B 1:3~1:4 Negative Online Inquiry

Background

PI4K2B Gene Knockout Cell Lines are expertly engineered cellular models designed to facilitate the study of the phosphatidylinositol 4-kinase type 2 beta (PI4K2B) gene's role in cellular processes. These knockout cell lines are created through precise genome editing techniques, ensuring that the PI4K2B gene is effectively disrupted, enabling researchers to analyze the consequences of its absence on various biochemical pathways and cellular functions.

The primary function of PI4K2B is the phosphorylation of phosphatidylinositol to generate phosphatidylinositol 4-phosphate, a critical lipid that participates in cellular signaling and membrane trafficking. By employing these knockout cell lines, scientists can delineate the specific contributions of PI4K2B to processes such as membrane dynamics, vesicle transport, and cellular signaling mechanisms. The ability to observe the phenotypic changes and alterations in signaling pathways provides invaluable insights into diseases where PI4K2B is implicated, including cancer and metabolic disorders.

In clinical and research settings, the cascading effects of PI4K2B deficiency can be explored, facilitating drug discovery and the development of therapeutic interventions targeting lipid signaling pathways. Available tools often fail to address the nuanced mechanisms involving specific genes; however, PI4K2B knockout cell lines offer a straightforward and targeted approach to investigating gene function.

What sets these cell lines apart from conventional models is their specificity and reproducibility. Researchers gain confidence in their experiments through the precise genetic alteration, allowing for consistent results across multiple studies. Moreover, the establishment of these models provides an essential resource for academic and pharmaceutical laboratories seeking deeper biological insights.

Our company is dedicated to advancing scientific knowledge by creating high-quality genetic models, backed by years of expertise in cellular biology and genomics. By integrating cutting-edge technology and a commitment to providing valuable research tools, we equip our users with the means to explore the complexities of gene function and their implications in health and disease.

Please note that all services are for research use only. Not intended for any clinical use.

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