Gene: PHYKPL
Official Full Name: 5-phosphohydroxy-L-lysine phospho-lyaseprovided by HGNC
Gene Summary: This is a nuclear gene encoding a mitochondrial enzyme that catalyzes the conversion of 5-phosphonooxy-L-lysine to ammonia, inorganic phosphate, and 2-aminoadipate semialdehyde. Mutations in this gene may cause phosphohydroxylysinuria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO24353 | PHYKPL Knockout cell line (HeLa) | Human | PHYKPL | 1:3~1:6 | Negative | Online Inquiry |
KO24354 | PHYKPL Knockout cell line (HCT 116) | Human | PHYKPL | 1:2~1:4 | Negative | Online Inquiry |
KO24355 | PHYKPL Knockout cell line (HEK293) | Human | PHYKPL | 1:3~1:6 | Negative | Online Inquiry |
KO24356 | PHYKPL Knockout cell line (A549) | Human | PHYKPL | 1:3~1:4 | Negative | Online Inquiry |
PHYKPL Gene Knockout Cell Lines are an advanced biotechnological tool designed for researchers and clinicians to investigate the functional role of the PHYKPL gene in various biological processes. These cell lines are engineered through CRISPR-Cas9 gene editing technologies to fully ablate the PHYKPL gene, allowing for a detailed study of its contributions to cellular physiology, signaling pathways, and related metabolic functions.
The primary mechanism of action for these knockout cell lines involves the disruption of the PHYKPL gene's coding sequence, leading to the absence of the corresponding protein product. This enables researchers to observe phenotypic changes and molecular responses in a controlled environment, thus providing invaluable insights into the gene's role in health and disease. Moreover, understanding the implications of PHYKPL ablation can facilitate the development of targeted therapies in diseases where this gene is implicated, including various metabolic disorders.
The scientific importance of PHYKPL Gene Knockout Cell Lines extends to both basic and applied research. These cell lines serve as crucial models for studying gene function, drug interactions, and the pathways associated with various physiological responses. They are particularly valuable in preclinical studies aimed at developing new therapeutic approaches, enabling researchers to uncover novel mechanisms of action and potential drug targets.
What sets our PHYKPL Gene Knockout Cell Lines apart from alternatives on the market is their unparalleled specificity and reliability. Developed under stringent quality control measures, these cell lines ensure consistent performance and reproducibility across experiments. Additionally, our cell lines are provided with comprehensive documentation and support, enabling seamless integration into research workflows.
In a rapidly advancing scientific field, the ability to manipulate genomic elements accurately is crucial. By offering PHYKPL Gene Knockout Cell Lines, we cater to the needs of both researchers and clinicians striving for a deeper understanding of gene function and its therapeutic implications. Our expertise in biological products positions us as a trusted partner in unlocking the complexities of molecular biology and enhancing research outcomes.
Please note that all services are for research use only. Not intended for any clinical use.
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