Gene: PHF7
Official Full Name: PHD finger protein 7provided by HGNC
Gene Summary: Spermatogenesis is a complex process regulated by extracellular and intracellular factors as well as cellular interactions among interstitial cells of the testis, Sertoli cells, and germ cells. This gene is expressed in the testis in Sertoli cells but not germ cells. The protein encoded by this gene contains plant homeodomain (PHD) finger domains, also known as leukemia associated protein (LAP) domains, believed to be involved in transcriptional regulation. The protein, which localizes to the nucleus of transfected cells, has been implicated in the transcriptional regulation of spermatogenesis. Alternate splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO22425 | PHF7 Knockout cell line (HeLa) | Human | PHF7 | 1:3~1:6 | Negative | Online Inquiry |
KO22426 | PHF7 Knockout cell line (HCT 116) | Human | PHF7 | 1:2~1:4 | Negative | Online Inquiry |
KO22427 | PHF7 Knockout cell line (HEK293) | Human | PHF7 | 1:3~1:6 | Negative | Online Inquiry |
KO22428 | PHF7 Knockout cell line (A549) | Human | PHF7 | 1:3~1:4 | Negative | Online Inquiry |
PHF7 Gene Knockout Cell Lines represent a cutting-edge tool in genomic research, engineered to specifically delete the PHF7 gene, a key player in various biological processes. These cell lines are created using advanced CRISPR-Cas9 technology, which allows for precise modifications in the genome, enabling researchers to study the phenotypic consequences of PHF7 loss-of-function in cellular models. By observing the changes in cellular behavior, signaling pathways, and gene expression profiles, scientists can gain critical insights into the role of PHF7 in health and disease.
The primary function of PHF7 Gene Knockout Cell Lines is to facilitate the exploration of gene function and interaction within diverse biological contexts. Researchers can utilize these cell lines to model diseases, therapeutic responses, and cellular mechanisms that are influenced by the PHF7 gene, thus accelerating discoveries related to oncogenesis, developmental biology, and other areas of interest. In clinical settings, understanding the implications of the PHF7 knockout could lead to novel targets for intervention in various conditions characterized by aberrant gene expression.
What sets our PHF7 Gene Knockout Cell Lines apart from alternatives is their high efficiency and reproducibility, ensuring reliable results across experiments. Unlike conventional knockout techniques, our CRISPR-based approach guarantees specificity and minimizes off-target effects, making these cell lines not only robust but also highly relevant for translational research.
For researchers and clinicians aiming to advance their understanding of genetic regulation and its impact on health, our PHF7 Gene Knockout Cell Lines offer invaluable insights into gene function while supporting a broad spectrum of applications from basic research to drug discovery. With years of expertise in genetic engineering and a commitment to quality, our company stands at the forefront of providing innovative biological products that enable scientific advancement and enhance research outcomes.
Please note that all services are for research use only. Not intended for any clinical use.
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