Gene: PHF23
Official Full Name: PHD finger protein 23provided by HGNC
Gene Summary: Predicted to enable metal ion binding activity. Involved in negative regulation of autophagosome assembly; negative regulation of autophagosome maturation; and positive regulation of protein ubiquitination. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO15183 | PHF23 Knockout cell line (HeLa) | Human | PHF23 | 1:3~1:6 | Negative | Online Inquiry |
KO15184 | PHF23 Knockout cell line (HCT 116) | Human | PHF23 | 1:2~1:4 | Negative | Online Inquiry |
KO15185 | PHF23 Knockout cell line (HEK293) | Human | PHF23 | 1:3~1:6 | Negative | Online Inquiry |
KO15186 | PHF23 Knockout cell line (A549) | Human | PHF23 | 1:3~1:4 | Negative | Online Inquiry |
PHF23 Gene Knockout Cell Lines are genetically modified cellular models designed to facilitate in-depth research on the phosphatase homolog protein 23 (PHF23). These cell lines have undergone targeted gene editing to eliminate the expression of the PHF23 gene, allowing researchers to study the functional consequences of PHF23 loss and its role in various biological processes, including cell signaling, gene regulation, and disease pathogenesis. The knockout mechanism is typically achieved through CRISPR/Cas9 technology, an advanced method that ensures specific and efficient gene disruption.
The primary function of PHF23 Gene Knockout Cell Lines is to provide a system for investigating the effects of PHF23 deficiency on cellular behavior and molecular pathways. By using these cell lines, researchers can explore alterations in gene expression profiles, protein interactions, and phenotypic changes that could be implicated in diseases such as cancer and neurodegeneration. These insights contribute to a broader understanding of PHF23's biological roles, potentially leading to the identification of new therapeutic targets.
The scientific importance of PHF23 Gene Knockout Cell Lines extends into both academic and clinical research settings. In vitro studies utilizing these cell lines help elucidate the complex interactions involved in cellular processes and disease mechanisms. Additionally, they serve as valuable tools for drug discovery and development, where understanding the role of specific genes can guide the identification of novel pharmacological interventions.
Compared to traditional cell lines, the PHF23 Gene Knockout Cell Lines offer unique advantages. They provide researchers with a more precise and reliable model to mimic disease conditions associated with PHF23 dysregulation. This specificity is key in generating reproducible results, streamlining the pathway from hypothesis to experimental validation. Moreover, the advanced gene editing technology used in developing these cell lines minimizes off-target effects, enhancing the reliability of experimental outcomes.
By integrating PHF23 Gene Knockout Cell Lines into their research, scientists and clinicians can significantly advance their understanding of PHF23-related pathways and expedite the search for targeted therapies. These cell lines empower researchers to make informed decisions and innovative discoveries that could translate into clinical applications.
Our company specializes in offering high-quality biological products, including genetically modified cell lines, backed by years of expertise in the field. We are committed to providing researchers with the critical tools they need to advance scientific knowledge and improve healthcare outcomes.
Please note that all services are for research use only. Not intended for any clinical use.
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