Gene: PDZRN3
Official Full Name: PDZ domain containing ring finger 3provided by HGNC
Gene Summary: This gene encodes a member of the LNX (Ligand of Numb Protein-X) family of RING-type ubiquitin E3 ligases. This protein may function in vascular morphogenesis and the differentiation of adipocytes, osteoblasts and myoblasts. This protein may be targeted for degradation by the human papilloma virus E6 protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO30021 | PDZRN3 Knockout cell line (HEK293) | Human | PDZRN3 | 1:3~1:6 | Negative | Online Inquiry |
PDZRN3 Gene Knockout Cell Lines are specialized cell lines that have undergone genetic modification to disrupt the PDZRN3 gene, a critical player in various cellular processes including signal transduction and cellular adhesion. These knockout lines serve as invaluable tools in the exploration of gene function and its implications in diverse biological contexts. The knockout mechanism is achieved through modern gene editing techniques such as CRISPR-Cas9, resulting in a complete loss of PDZRN3 protein expression, which allows researchers to meticulously study the phenotypic changes associated with the absence of this gene.
The PDZRN3 gene has been implicated in numerous physiological processes and diseases, making these cell lines essential for understanding the underlying mechanisms of disorders such as cancer, neurodegeneration, and developmental anomalies. They provide a platform for investigating the role of PDZRN3 in signaling pathways and cellular interactions, data that has profound implications for therapeutic development and precision medicine.
Compared to alternative models, such as those relying on RNA interference, PDZRN3 Gene Knockout Cell Lines offer a more stable, long-term solution for studying gene function since the knockout is permanent. This stability ensures more reproducible and consistent results across experiments. Additionally, these cell lines facilitate high-throughput screening and allow the assessment of functional genomics in a controlled environment.
For researchers and clinicians, these knockout cell lines provide a powerful resource, enabling them to delve into the complexities of cellular mechanisms with confidence. As experts in biological product development, our company is committed to advancing the fields of genetics and molecular biology, continuously delivering high-quality tools that empower groundbreaking research and foster innovation in scientific inquiry. By incorporating our PDZRN3 Gene Knockout Cell Lines into your studies, you can accelerate the pace of discovery while enhancing the reproducibility and reliability of your findings.
Please note that all services are for research use only. Not intended for any clinical use.
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