Gene: PDZD2
Official Full Name: PDZ domain containing 2provided by HGNC
Gene Summary: The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis. [provided by RefSeq, Dec 2015]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO29979 | PDZD2 Knockout cell line (HeLa) | Human | PDZD2 | 1:3~1:6 | Negative | Online Inquiry |
PDZD2 Gene Knockout Cell Lines represent a significant advancement in cellular biology and genetic studies. These cell lines have been genetically modified to produce a complete knockout of the PDZD2 gene, effectively eliminating its expression and providing a unique tool for researchers interested in investigating the functions associated with this gene. The PDZD2 gene is implicated in various biological processes, including cellular signaling and protein interactions, making its knockout critical for elucidating its role in health and disease.
The primary function of the PDZD2 Gene Knockout Cell Lines is to facilitate the study of downstream effects resulting from the loss of PDZD2 expression. This is achieved through methodologies such as Western blotting, gene expression profiling, and functional assays, allowing researchers to observe changes in cellular behavior, signaling pathways, and metabolic processes. The knockout model thus serves as an essential platform for dissecting the role of PDZD2 in both normal physiological processes and pathological states, including cancer and neurodegenerative diseases.
Scientifically, PDZD2 Gene Knockout Cell Lines are invaluable in both academic research and clinical settings, where understanding gene function can lead to breakthroughs in therapeutics and diagnostics. These cell lines can be utilized for drug screening, disease modeling, and understanding gene-environment interactions, providing vital insights that can inform treatment strategies.
Compared to alternatives, such as CRISPR-edited or siRNA-mediated knockdowns, our PDZD2 Gene Knockout Cell Lines offer a stable and permanent loss of gene function, yielding reproducible results across experiments. This stability is critical for long-term studies and helps mitigate issues related to transient expression or incomplete gene silencing.
For researchers and clinicians seeking reliable and well-characterized cell models, the value of PDZD2 Gene Knockout Cell Lines cannot be overstated. They provide an unprecedented opportunity to explore gene function in a controlled environment, significantly contributing to our understanding of fundamental biological processes.
Our company takes pride in offering high-quality biological products backed by state-of-the-art technology and extensive expertise in genetic engineering. We are committed to supporting the scientific community by delivering innovative solutions that empower research and advance knowledge in the field of molecular and cellular biology.
Please note that all services are for research use only. Not intended for any clinical use.
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