Gene: PDSS2
Official Full Name: decaprenyl diphosphate synthase subunit 2provided by HGNC
Gene Summary: The protein encoded by this gene is an enzyme that synthesizes the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. The gene product catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis. Defects in this gene are a cause of coenzyme Q10 deficiency.[provided by RefSeq, Oct 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO15255 | PDSS2 Knockout cell line (HeLa) | Human | PDSS2 | 1:3~1:6 | Negative | Online Inquiry |
KO15256 | PDSS2 Knockout cell line (HCT 116) | Human | PDSS2 | 1:2~1:4 | Negative | Online Inquiry |
KO15257 | PDSS2 Knockout cell line (HEK293) | Human | PDSS2 | 1:3~1:6 | Negative | Online Inquiry |
KO15258 | PDSS2 Knockout cell line (A549) | Human | PDSS2 | 1:3~1:4 | Negative | Online Inquiry |
PDSS2 Gene Knockout Cell Lines represent a powerful tool for researchers aiming to elucidate the functional roles of the PDSS2 gene in various biological processes. These specialized cell lines have been genetically engineered to knock out the expression of PDSS2, a gene involved in several critical metabolic pathways, including the biosynthesis of coenzyme Q10 (ubiquinone). By eliminating PDSS2 expression, these cell lines allow scientists to investigate the downstream effects on cellular metabolism, oxidative stress responses, and mitochondrial function.
The primary function of PDSS2 Gene Knockout Cell Lines is to serve as a model for examining the implications of PDSS2 deficiency in both laboratory and clinical contexts. The precise mechanisms of action involve assessing changes in metabolic profiles, reactive oxygen species (ROS) production, and other cellular stress indicators, subsequently providing insights into diseases associated with mitochondrial dysfunction, such as neurodegenerative disorders and cardiovascular diseases.
From a scientific standpoint, the use of PDSS2 knockout models is invaluable. These cell lines enable the investigation of therapeutic targets and the development of potential treatments aimed at conditions linked to mitochondrial abnormalities. They also facilitate advancements in personalized medicine by allowing researchers to tailor approaches based on an individual's genetic background.
One of the key advantages of using PDSS2 Gene Knockout Cell Lines is their specificity and reliability compared to alternative knockout models or RNA interference methods, which may not completely abrogate gene function. Additionally, the characterization of these cell lines ensures reproducibility and consistency in experiments, significantly enhancing research outcomes.
For researchers and clinicians, the value of PDSS2 Gene Knockout Cell Lines lies in their ability to foster a deeper understanding of metabolic pathways and to drive innovation in therapeutic strategies. By utilizing these advanced cell lines, scientists can expedite research processes, leading to groundbreaking discoveries that have the potential to transform disease treatment modalities.
Our company is committed to providing cutting-edge research tools, empowering scientists worldwide with high-quality products like PDSS2 Gene Knockout Cell Lines to accelerate their contributions to biomedical research.
Please note that all services are for research use only. Not intended for any clinical use.
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