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PDP2 Knockout Cell Lines

Gene: PDP2

Official Full Name: pyruvate dehydrogenase phosphatase catalytic subunit 2provided by HGNC

Gene Summary: This gene is a mitochondrial protein that functions as a phosphatase and is involved in the enzymatic resetting of the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Aug 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO15263 PDP2 Knockout cell line (HeLa) Human PDP2 1:3~1:6 Negative Online Inquiry
KO15264 PDP2 Knockout cell line (HCT 116) Human PDP2 1:2~1:4 Negative Online Inquiry
KO15265 PDP2 Knockout cell line (HEK293) Human PDP2 1:3~1:6 Negative Online Inquiry
KO15266 PDP2 Knockout cell line (A549) Human PDP2 1:3~1:4 Negative Online Inquiry

Background

PDP2 Gene Knockout Cell Lines are a meticulously engineered tool designed for advanced genetic research, providing scientists with a powerful means to study the function and regulatory mechanisms of the PDP2 gene, which is implicated in various metabolic processes and neurological functions. These cell lines are created using CRISPR-Cas9 technology, which allows for precise deletion of the PDP2 gene, facilitating in-depth analysis of its role in cellular pathways related to energy metabolism, cell signaling, and developmental processes.

The key function of PDP2 Gene Knockout Cell Lines lies in their ability to serve as a model for understanding the gene's contribution to cellular homeostasis and disease states. By creating a complete loss-of-function scenario, researchers can assess phenotypic changes, evaluate metabolic shifts, and explore compensatory mechanisms within affected pathways. Such insights are invaluable for elucidating the underlying mechanisms of diseases such as neurological disorders, where PDP2 modulation may play a critical role.

From a scientific standpoint, these knockout cell lines are crucial in various research applications, including drug discovery, toxicity testing, and basic cellular biology studies. They offer a reliable platform for assessing the impact of potential therapeutic compounds on cells lacking the PDP2 gene, providing essential data for developing novel treatments.

One of the unique selling points of our PDP2 Gene Knockout Cell Lines is their high efficiency and reproducibility compared to conventional knockout methods. Our proprietary optimization process ensures consistent performance across experiments, significantly reducing variability and accelerating the pace of research. Furthermore, comprehensive characterization and validation studies accompany each product batch, guaranteeing that users receive high-quality, reliable tools for their investigations.

For researchers and clinicians, the value of PDP2 Gene Knockout Cell Lines extends beyond simplicity; they represent a leap forward in understanding complex biological processes, ultimately guiding the development of effective therapies and advancing the field of molecular biology. As a leader in biological product offerings, our company is dedicated to supporting innovative research with robust solutions, ensuring that scientists can obtain accurate, reliable data while pushing the boundaries of what is known in the life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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