Gene: PAMR1
Official Full Name: peptidase domain containing associated with muscle regeneration 1provided by HGNC
Gene Summary: Predicted to enable calcium ion binding activity and serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO28676 | PAMR1 Knockout cell line (HEK293) | Human | PAMR1 | 1:3~1:6 | Negative | Online Inquiry |
PAMR1 Gene Knockout Cell Lines are specifically engineered cell lines that exhibit the complete knockout of the PAMR1 gene, a critical component implicated in various biological processes and disease mechanisms. These cell lines are generated using advanced CRISPR/Cas9 technology, which allows for precise editing of the genome, ensuring that researchers can study the specific effects of PAMR1 loss-of-function in a controlled environment.
The key function of PAMR1 Gene Knockout Cell Lines lies in their ability to facilitate the direct exploration of the PAMR1 gene's role in cell signaling, differentiation, and response to pharmacological agents. By eliminating the gene's expression, researchers can dissect downstream pathways and interactions that contribute to both physiological and pathological states. This makes these cell lines invaluable for studies focused on cancer biology, immune response, and cellular metabolism.
From a scientific perspective, PAMR1 Gene Knockout Cell Lines are crucial for advancing our understanding of gene function in various human diseases. Their applications extend to drug discovery and development, where they can serve as models to identify new therapeutic targets or to elucidate mechanisms of drug resistance. In clinical settings, these cell lines can also be used for the evaluation of gene therapies designed to compensate or correct the function of the PAMR1 gene.
One of the standout advantages of our PAMR1 Gene Knockout Cell Lines is their unrivaled specificity and reliability compared to traditional siRNA or shRNA methods, which often lead to off-target effects or incomplete knockdown. Additionally, the robust validation of these cell lines, characterized by extensive phenotypic and genotypic assessments, ensures reproducibility across different research environments.
For researchers and clinicians seeking to explore the intricacies of gene functions and their roles in disease, the PAMR1 Gene Knockout Cell Lines offer a unique and powerful tool. Our commitment to delivering high-quality biological products, combined with our expertise in gene editing technologies, positions us as a trusted partner in scientific research and innovation. By choosing our PAMR1 Gene Knockout Cell Lines, users can enhance their research outcomes and accelerate discoveries in gene function and therapeutic development.
Please note that all services are for research use only. Not intended for any clinical use.
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