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OTX1 Knockout Cell Lines

Gene: OTX1

Official Full Name: orthodenticle homeobox 1provided by HGNC

Gene Summary: This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mouse is required for proper brain and sensory organ development and can cause epilepsy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO36257 OTX1 Knockout cell line (HeLa) Human OTX1 1:3~1:6 Negative Online Inquiry
KO36258 OTX1 Knockout cell line (HCT 116) Human OTX1 1:2~1:4 Negative Online Inquiry
KO36259 OTX1 Knockout cell line (HEK293) Human OTX1 1:3~1:6 Negative Online Inquiry
KO36260 OTX1 Knockout cell line (A549) Human OTX1 1:3~1:4 Negative Online Inquiry

Background

OTX1 Gene Knockout Cell Lines are innovative biological tools engineered to specifically eliminate the OTX1 gene's expression from cellular environments, allowing for the detailed investigation of OTX1's role in various biological processes. The OTX1 gene plays a pivotal role in regulating development and cellular differentiation, making these knockout cell lines invaluable for dissecting its function in both physiological and pathological contexts.

These cell lines operate through precise genetic editing techniques such as CRISPR-Cas9, which introduces targeted mutations in the OTX1 gene, effectively disrupting protein expression. This disruption can illuminate the implications of OTX1 deficiency in critical pathways, including development and oncogenesis, by facilitating comparative analyses against wild-type cell lines.

In research settings, OTX1 Gene Knockout Cell Lines are crucial for understanding the gene’s role in specific cancers, neurodevelopmental disorders, and regenerative medicine, thereby pushing the boundaries of current scientific knowledge. Clinically, they enable researchers to develop and test novel therapeutic strategies targeting OTX1, marking a significant step toward precision medicine.

Compared to alternative models, such as transient knockdowns, these stable cell lines provide a consistent and reliable platform for long-term studies, reducing variability in experimental outcomes. Researchers can achieve reproducibility and enhanced data integrity, fostering more robust conclusions.

The value of OTX1 Gene Knockout Cell Lines is further underscored by their potential to accelerate discovery and innovation in both academic and industrial laboratories. Our company specializes in providing high-quality genetic models designed with precision and reliability in mind, ensuring that researchers and clinicians have access to the best tools for advancing their work.

Please note that all services are for research use only. Not intended for any clinical use.

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