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OTUD6B Knockout Cell Lines

Gene: OTUD6B

Official Full Name: OTU deubiquitinase 6Bprovided by HGNC

Gene Summary: This gene encodes a member of the ovarian tumor domain (OTU)-containing subfamily of deubiquitinating enzymes. Deubiquitinating enzymes are primarily involved in removing ubiquitin from proteins targeted for degradation. This protein may function as a negative regulator of the cell cycle in B cells. [provided by RefSeq, Nov 2013]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO22348 OTUD6B Knockout cell line (HeLa) Human OTUD6B 1:3~1:6 Negative Online Inquiry
KO22349 OTUD6B Knockout cell line (HCT 116) Human OTUD6B 1:2~1:4 Negative Online Inquiry
KO22350 OTUD6B Knockout cell line (HEK293) Human OTUD6B 1:3~1:6 Negative Online Inquiry
KO22351 OTUD6B Knockout cell line (A549) Human OTUD6B 1:3~1:4 Negative Online Inquiry

Background

OTUD6B Gene Knockout Cell Lines are genetically modified human cell lines specifically designed for the targeted disruption of the OTUD6B gene, which is critical in regulating various cellular functions, including protein ubiquitination and the response to DNA damage. By utilizing the CRISPR-Cas9 genome-editing technology, these cell lines provide researchers with a unique tool for studying the responses of cellular pathways involved in cancer progression, immune responses, and other physiological processes.

The primary function of OTUD6B gene knockout cell lines is to elucidate the biological role that OTUD6B plays in cellular mechanisms. By completely knocking out the gene, researchers can observe the resultant phenotypic changes and alterations in signaling pathways, thus enabling a deeper understanding of its contributions to pathology. This is invaluable in both basic research and translational studies, as it aids in the identification of potential therapeutic targets and biomarkers for diseases where OTUD6B is implicated.

The scientific significance of these cell lines is underscored by their application in cancer research, where dysregulation of ubiquitination processes is linked to tumorigenesis. Additionally, the knockout models can be employed in drug development and efficacy studies, providing insights into how targeting the OTUD6B pathway might offer novel therapeutic strategies.

One of the primary advantages of our OTUD6B Gene Knockout Cell Lines is their validation and reliability; each line undergoes rigorous characterization to ensure accurate gene editing and consistent performance across experiments. Compared to traditional knockdown approaches, which provide transient effects, these knockout cell lines facilitate long-term studies and reproducible results, making them a preferable choice for researchers seeking robust experimental systems.

In the current landscape of biomedical research, the availability of specialized cell lines such as these stands as a critical asset for those aiming to drive innovative discoveries. Our company prides itself on a commitment to precision in genetic engineering and extensive experience in providing high-quality biological products that cater to the specific needs of the scientific community. We understand the complexities of research demands and strive to empower researchers and clinicians with reliable tools that contribute to advancing knowledge and therapeutic development.

Please note that all services are for research use only. Not intended for any clinical use.

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