Gene: OR51I2
Official Full Name: olfactory receptor family 51 subfamily I member 2provided by HGNC
Gene Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO25819 | OR51I2 Knockout cell line (HCT 116) | Human | OR51I2 | 1:2~1:4 | Negative | Online Inquiry |
OR51I2 Gene Knockout Cell Lines are specialized cell cultures in which the OR51I2 gene has been deliberately disrupted or "knocked out." This genetic modification allows researchers to study the specific functions and regulatory mechanisms associated with the OR51I2 gene, which is known to play a significant role in olfactory signaling pathways. By enabling the selective elimination of this gene, these knockout cell lines serve as critical tools in elucidating the cellular processes influenced by OR51I2, particularly in the context of chemosensory responses and potential implications in olfactory-related disorders.
The primary function of the OR51I2 knockout cell lines is to provide a controlled experimental environment where the impact of OR51I2 absence can be observed. Researchers can investigate changes in cellular behavior, signaling cascades, and gene expression profiles that occur due to the loss of OR51I2 function. These insights can be integral in understanding the contribution of this gene to various physiological processes and potentially identify novel therapeutic targets for conditions related to olfaction.
The scientific importance of these knockout cell lines extends into both basic and translational research. In basic research, they facilitate a deeper understanding of olfactory mechanisms, while in clinical settings, they hold potential for discovering targeted interventions for olfactory dysfunction or other associated disorders. The availability of such models accelerates the pace of research by providing clear, reproducible data that can inform future studies and therapeutic strategies.
Comparatively, OR51I2 Gene Knockout Cell Lines stand out due to their specificity and reliability. Unlike other genetically modified cell lines that may exhibit off-target effects, these knockout lines offer precise control over the genetic manipulation of the OR51I2 gene, ensuring that results are both valid and consistent. They are also compatible with a variety of assay systems, making them versatile tools in diverse experimental setups.
For researchers and clinicians invested in olfactory research or related fields, these knockout cell lines are invaluable for unraveling complex biological phenomena. By utilizing this product, users can advance their understanding of olfactory signaling and contribute to the ongoing quest for innovative therapeutic solutions.
Our company specializes in providing high-quality biological products, including genetically modified cell lines that are designed with the utmost precision and backed by extensive analytical validation. We are committed to supporting your research endeavors with tools that enhance scientific discovery and clinical applications.
Please note that all services are for research use only. Not intended for any clinical use.
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