Gene: OR51I1
Official Full Name: olfactory receptor family 51 subfamily I member 1provided by HGNC
Gene Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO25820 | OR51I1 Knockout cell line (HCT 116) | Human | OR51I1 | 1:2~1:4 | Negative | Online Inquiry |
OR51I1 Gene Knockout Cell Lines are cutting-edge cellular models specifically engineered to study the functions and effects of the OR51I1 gene, which is implicated in various biological processes including olfactory signaling and potential roles in cancer biology. By utilizing CRISPR-Cas9 technology, these cell lines have been rendered deficient in the OR51I1 gene, providing unique tools for investigating gene function, signaling pathways, and the broader implications of OR51I1 in health and disease.
The key mechanisms at play in these knockout cell lines revolve around their ability to elucidate the role of OR51I1 in cellular responses to external stimuli and its potential impact on physiological processes. Researchers can utilize these models to dissect the gene’s contributions to chemosensory signaling and to explore novel therapeutic targets that may arise from altered signaling pathways. In addition to their use in fundamental research, these cell lines have significant implications in understanding pathological states where OR51I1 expression may be altered.
The scientific importance of OR51I1 Gene Knockout Cell Lines extends to their applications in both basic and clinical research settings. They provide a critical platform for screening drug responses, investigating biomarker potentials, and elucidating the mechanisms of disease progression linked to OR51I1 dysregulation. Compared to conventional cell lines that express the OR51I1 gene, these knockout models afford a unique opportunity to capture the very essence of gene function free from confounding endogenous expression.
The advantages of using OR51I1 Gene Knockout Cell Lines over available alternatives include their precision in gene editing, which reduces variability, and the profound insights they can yield into the role of OR51I1 in diverse biological contexts. These cell lines are valuable to researchers, clinicians, and pharmaceutical developers aiming to advance their explorations into olfactory mechanisms, cancer biology, and potential therapeutic interventions.
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Please note that all services are for research use only. Not intended for any clinical use.
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