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OR51B5 Knockout Cell Lines

Gene: OR51B5

Official Full Name: olfactory receptor family 51 subfamily B member 5provided by HGNC

Gene Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO15449 OR51B5 Knockout cell line (HCT 116) Human OR51B5 1:2~1:4 Negative Online Inquiry

Background

OR51B5 Gene Knockout Cell Lines are genetically engineered cellular models specifically designed to facilitate the study of the OR51B5 gene's function and its implications in various biological processes. The OR51B5 gene encodes for a putative olfactory receptor that is thought to have significant roles beyond the olfactory system, potentially influencing pathways related to oncogenesis and neurobiology. These knockout cell lines serve as critical tools for elucidating the gene's mechanisms and contributions to cellular signaling.

The primary function of these cell lines is to allow researchers to observe the consequences of the absence of the OR51B5 gene. By utilizing CRISPR/Cas9 gene-editing technology, the knockout is precise, enabling the investigation of phenotypic changes, receptor signaling pathways, and interactions with other molecular players. This targeted approach provides insights into how OR51B5 may influence physiological and pathological processes, making it invaluable for both academic research and clinical studies.

The scientific importance of OR51B5 Gene Knockout Cell Lines lies in their role in advancing our understanding of olfactory receptors and their non-canonical roles in various diseases. With growing interest in therapeutic targets that deviate from traditional notions of receptor functionality, this product is particularly relevant for researchers probing into cancer biology, neurodegenerative diseases, and sensory biology.

One of the unique selling points of these cell lines is their specificity and reliability. Many other available models may not accurately represent the true effect of gene knockout, but our meticulously developed cell lines ensure high efficiency and reproducibility in experimental settings. Additionally, the rigorous validation of these lines against a robust set of controls provides users with confidence in their experimental outcomes.

For researchers and clinicians focusing on the molecular dynamics of olfactory receptors and their broader implications, OR51B5 Gene Knockout Cell Lines present an exceptional value. They offer an innovative approach to dissect complex biological questions, subsequently paving the way for novel therapeutic strategies.

Our company is dedicated to providing high-quality genetic tools that empower scientific discovery. With our expertise in cell line engineering and commitment to supporting researchers, we deliver products that drive advancements in biological research and clinical applications.

Please note that all services are for research use only. Not intended for any clinical use.

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