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OR13C7 Knockout Cell Lines

Gene: OR13C7

Official Full Name: olfactory receptor family 13 subfamily C member 7 (gene/pseudogene)provided by HGNC

Gene Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jan 2017]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO25811 OR13C7 Knockout cell line (HeLa) Human OR13C7 1:3~1:6 Negative Online Inquiry
KO25812 OR13C7 Knockout cell line (HCT 116) Human OR13C7 1:2~1:4 Negative Online Inquiry
KO25813 OR13C7 Knockout cell line (HEK293) Human OR13C7 1:3~1:6 Negative Online Inquiry
KO25814 OR13C7 Knockout cell line (A549) Human OR13C7 1:3~1:4 Negative Online Inquiry

Background

OR13C7 Gene Knockout Cell Lines are engineered cellular models specifically designed to study the function of the OR13C7 gene, which encodes a member of the olfactory receptor family. By utilizing CRISPR-Cas9 technology, these cell lines have been meticulously developed to ensure the complete knockout of OR13C7, allowing researchers to explore its biological role and implications in various physiological processes.

The key functionality of these cell lines lies in their ability to provide insights into the signaling pathways activated by olfactory receptors in non-neuronal contexts. Understanding how OR13C7 interacts with endogenous ligands can unveil its contributions to processes such as neuroinflammation, cancer progression, and cellular communication. The deletion of this gene aids in elucidating the receptor's native functions and the potential ramifications of its dysregulation.

These knockout cell lines hold significant scientific importance, particularly in translational research and drug discovery sectors. Researchers can employ them to screen for potential therapeutic compounds that may influence OR13C7-mediated pathways or to explore novel interactions with other cellular entities, paving the way for innovative treatment strategies in diseases linked to olfactory receptor disorders.

What sets OR13C7 Gene Knockout Cell Lines apart from traditional cell models is their specificity and precision in targeting the OR13C7 gene. This unique offering allows for unparalleled fidelity in functional assays and eliminates off-target effects often observed in less refined genetic manipulations. Additionally, these cell lines come fully validated to ensure consistency and reproducibility in experimental outcomes.

The value of these gene knockout cell lines cannot be overstated for researchers and clinicians focused on olfactory signaling and its broader implications in health and disease. They serve as a critical tool in advancing our understanding of complex biological systems while guiding the development of novel therapeutic interventions.

Our company, with its extensive background in cutting-edge genetic engineering and cell line development, offers a comprehensive portfolio of biological products that empower research and catalyze discoveries in life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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