Gene: ODAD1
Official Full Name: outer dynein arm docking complex subunit 1provided by HGNC
Gene Summary: This gene encodes a coiled-coil domain-containing protein that is a component of the outer dynein arm docking complex in cilia cells. Mutations in this gene may cause primary ciliary dyskinesia 20. [provided by RefSeq, May 2013]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO15536 | ODAD1 Knockout cell line (HEK293) | Human | ODAD1 | 1:3~1:6 | Negative | Online Inquiry |
ODAD1 Gene Knockout Cell Lines are engineered cellular models specifically designed to study the function of the ODAD1 gene, a critical component in various biological processes including cell differentiation, immune response, and tumorigenesis. The gene knockout technique involves the targeted disruption of the ODAD1 gene, resulting in the loss of its encoded protein. This system allows researchers to dissect the molecular pathways modulated by ODAD1, providing insights into cellular behavior and disease mechanisms.
The primary function of the ODAD1 Gene Knockout Cell Lines lies in their ability to facilitate the study of gene function by eliminating ODAD1 expression. Through genomic editing technologies such as CRISPR-Cas9, these cell lines enable researchers to analyze phenotypic changes, assess signaling pathways, and explore compensatory mechanisms that may arise from the gene's absence. By comparing the knockout cells with wild-type controls, scientists can elucidate the gene's contributions to specific biological processes and its implications in various pathologies.
The scientific importance of these cell lines extends to both basic research and clinical applications. For instance, they hold significant potential in cancer research, where the ODAD1 gene may play a role in tumor progression and response to therapies. Investigators can use these models to identify therapeutic targets and investigate the efficacy of new treatment strategies in drug development.
One of the key advantages of using ODAD1 Gene Knockout Cell Lines is the precision of gene editing, offering a clear advantage over traditional methods such as RNA interference or overexpression systems. These knockout models provide more definitive experimental outcomes, aiding in the reduction of variability associated with incomplete gene targeting or off-target effects. Additionally, they are versatile and can be adapted to diverse cell types, making them suitable for a wide range of experimental setups.
For researchers and clinicians, the ability to explore gene function through these advanced cellular models is invaluable. They offer a unique opportunity to generate hypotheses that can translate into clinical applications, bridging the gap between laboratory findings and patient care.
Our company specializes in providing high-quality biological tools and resources for the research community. With a commitment to advancing scientific discovery, we are dedicated to delivering innovative solutions that empower researchers to unravel complex biological systems and contribute meaningfully to their fields.
Please note that all services are for research use only. Not intended for any clinical use.
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