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NRM Knockout Cell Lines

Gene: NRM

Official Full Name: nurimprovided by HGNC

Gene Summary: The protein encoded by this gene contains transmembrane domains and resides within the inner nuclear membrane, where it is tightly associated with the nucleus. This protein shares homology with isoprenylcysteine carboxymethyltransferase enzymes. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO31006 NRM Knockout cell line (HeLa) Human NRM 1:3~1:6 Negative Online Inquiry
KO31007 NRM Knockout cell line (HCT 116) Human NRM 1:2~1:4 Negative Online Inquiry
KO31008 NRM Knockout cell line (HEK293) Human NRM 1:3~1:6 Negative Online Inquiry
KO31009 NRM Knockout cell line (A549) Human NRM 1:3~1:4 Negative Online Inquiry

Background

NRM Gene Knockout Cell Lines represent a significant advancement in genetic research, providing a highly valuable tool for the study of gene function and disease mechanisms. These cell lines are meticulously engineered to contain specific gene disruptions through CRISPR/Cas9 technology, enabling the elucidation of gene roles in cellular processes, signaling pathways, and pathophysiological conditions.

The primary function of NRM Gene Knockout Cell Lines revolves around their ability to serve as model systems that mimic the loss-of-function mutations commonly observed in various diseases. The knockout mechanism involves precise editing of the target gene, often leading to a complete absence of protein expression or its functional activity, which helps researchers to delineate the biological consequences of gene loss. This is particularly relevant in areas such as cancer research, neurobiology, and drug development, where understanding the underlying genetic alterations is crucial for therapeutic intervention.

In terms of scientific importance, these cell lines are invaluable for both academic and clinical research applications, facilitating targeted drug screening, functional genomics studies, and the development of personalized medicine strategies. They offer a unique opportunity to validate gene targets before moving to in vivo studies, significantly enhancing the translational relevance of experimental data.

Compared to other gene knockout methods, NRM Gene Knockout Cell Lines provide superior specificity, reliability, and ease of use. Their validated background ensures that researchers can focus on the functional aspects of their genes of interest without sacrificing experimental integrity or reproducibility.

The value of NRM Gene Knockout Cell Lines lies not only in their ability to foster a deeper understanding of genetic functions but also in their potential to catalyze significant breakthroughs in translational research and therapeutic development. Additionally, our company prides itself on a legacy of excellence in genetic engineering technologies, backed by a team of experts dedicated to delivering high-quality biological products tailored to meet the evolving needs of researchers and clinicians. We aim to empower your research with innovative solutions that facilitate groundbreaking discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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