Gene: NIN
Official Full Name: nineinprovided by HGNC
Gene Summary: This gene encodes one of the proteins important for centrosomal function. This protein is important for positioning and anchoring the microtubules minus-ends in epithelial cells. Localization of this protein to the centrosome requires three leucine zippers in the central coiled-coil domain. Multiple alternatively spliced transcript variants that encode different isoforms have been reported. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO22878 | NIN Knockout cell line (HeLa) | Human | NIN | 1:3~1:6 | Negative | Online Inquiry |
KO22879 | NIN Knockout cell line (HCT 116) | Human | NIN | 1:2~1:4 | Negative | Online Inquiry |
KO22880 | NIN Knockout cell line (HEK293) | Human | NIN | 1:3~1:6 | Negative | Online Inquiry |
KO22881 | NIN Knockout cell line (A549) | Human | NIN | 1:3~1:4 | Negative | Online Inquiry |
NIN Gene Knockout Cell Lines are a specialized line of cultured cells in which the NIN (Nima-related kinase) gene has been precisely disrupted through targeted genetic manipulation techniques such as CRISPR-Cas9. These cell lines serve as powerful tools for studying the physiological and biochemical roles of the NIN gene, which is implicated in various cellular processes, including cell cycle regulation and tumorigenesis.
The key function of the NIN gene knockout is to facilitate the investigation of the specific biological pathways that are affected by the absence of NIN protein. Researchers can employ these cell lines to examine changes in cell proliferation, differentiation, and apoptosis, thereby elucidating the role of NIN in cancer development and progression. The mechanisms underlying these processes can be explored further using gene expression analysis, proteomics, and other advanced cellular assays, enabling a comprehensive understanding of how NIN influences cellular behavior.
In both research and clinical settings, the development of NIN Gene Knockout Cell Lines holds significant scientific value. They are ideal for drug discovery, as they allow researchers to identify potential therapeutic targets and biomarkers associated with altered NIN signaling. Additionally, these cell lines provide an excellent platform for testing the efficacy of novel compounds aimed at modulating NIN-related pathways.
Compared to alternative gene knockout models, our NIN Gene Knockout Cell Lines stand out due to their precise genetic modification and high stability, which ensures reproducible results. The ease of use and compatibility with a wide range of analysis methods further enhance their utility in experimental workflows.
By offering NIN Gene Knockout Cell Lines, we empower researchers and clinicians to uncover critical insights into the pathophysiological roles of NIN in disease contexts. Our company is committed to providing high-quality biological products backed by extensive expertise in genetic engineering and cell line development, ensuring that your research capabilities are fortified with the most reliable tools available.
Please note that all services are for research use only. Not intended for any clinical use.
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