Home / NECAB1 Knockout Cell Lines

NECAB1 Knockout Cell Lines

Gene: NECAB1

Official Full Name: N-terminal EF-hand calcium binding protein 1provided by HGNC

Gene Summary: Enables identical protein binding activity. Predicted to be involved in regulation of amyloid precursor protein biosynthetic process. Predicted to act upstream of or within blastocyst hatching. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO15788 NECAB1 Knockout cell line (HeLa) Human NECAB1 1:3~1:6 Negative Online Inquiry
KO15789 NECAB1 Knockout cell line (HEK293) Human NECAB1 1:3~1:6 Negative Online Inquiry

Background

NECAB1 Gene Knockout Cell Lines are genetically engineered cell lines in which the NECAB1 gene has been inactivated, providing a valuable tool for researchers studying the specific roles of this gene in cellular processes. The NECAB1 protein, known for its involvement in neuronal development and synaptic function, plays a critical role in various biological pathways, making these knockout cell lines essential for elucidating its contributions to health and disease.

The mechanism by which these cell lines function is predicated on the targeted disruption of the NECAB1 gene, achieved through advanced CRISPR-Cas9 gene-editing technology. This approach allows for precise removal of the gene sequence, leading to loss of protein expression and enabling researchers to observe the resultant phenotypic changes. Consequently, these cell lines serve as an invaluable resource for functional studies, enabling an intricate understanding of NECAB1's contributions to cellular signaling, neuronal differentiation, and potential pathologies, such as neurodegenerative disorders.

The scientific importance of NECAB1 Gene Knockout Cell Lines lies in their ability to facilitate groundbreaking research in the fields of neurobiology and cell signaling. They offer insights into complex mechanisms governing neuronal health, making them a critical asset in both academic and clinical settings where understanding the molecular basis of diseases is paramount. By utilizing these cell lines, researchers can advance drug discovery efforts and develop targeted therapies aimed at mitigating the effects of diseases associated with NECAB1 malfunction.

When compared to other genetic models, our NECAB1 Gene Knockout Cell Lines stand out due to their reliability, ease of use, and high reproducibility. Unlike conventional knockout strategies that may exhibit compensation effects or variability, our CRISPR-engineered lines provide a clean and specific genetic alteration that allows for more accurate interpretation of experimental results.

In summary, NECAB1 Gene Knockout Cell Lines represent a cutting-edge resource for researchers and clinicians aiming to unlock the complexities of gene function and disease mechanisms. Our company prides itself on delivering high-quality biological products backed by extensive expertise in molecular biology and genetics, ensuring that our customers have access to the most effective tools for their research and clinical innovations.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.