Home / NDFIP2 Knockout Cell Lines

NDFIP2 Knockout Cell Lines

Gene: NDFIP2

Official Full Name: Nedd4 family interacting protein 2provided by HGNC

Gene Summary: Enables WW domain binding activity. Involved in negative regulation of transport and regulation of macromolecule metabolic process. Located in several cellular components, including Golgi apparatus; mitochondrion; and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00497 NDFIP2 Knockout cell line (HCT 116) Human NDFIP2 1:2~1:4 Negative Online Inquiry
KO04520 NDFIP2 Knockout cell line (HeLa) Human NDFIP2 1:3~1:6 Negative Online Inquiry
KO04521 NDFIP2 Knockout cell line (HEK293) Human NDFIP2 1:3~1:6 Negative Online Inquiry
KO04522 NDFIP2 Knockout cell line (A549) Human NDFIP2 1:3~1:4 Negative Online Inquiry

Background

NDFIP2 Gene Knockout Cell Lines are specialized cellular models engineered to lack the NDFIP2 gene, a crucial component of multiple signaling pathways involved in cellular regulation and immune responses. These knockout cell lines are created using advanced gene-editing technologies, such as CRISPR/Cas9, which allow for precise modifications, ensuring that researchers have a reliable tool to investigate the functional roles of the NDFIP2 protein in various biological processes.

The primary function of NDFIP2 involves regulating the immune response, particularly through its interactions with ubiquitin ligases that modulate protein degradation and turnover. By employing these knockout cell lines, scientists can elucidate the pathways influenced by NDFIP2, particularly its role in inflammation and immune cell activation. The ability to study these alterations in a controlled environment makes NDFIP2 knockout cell lines pivotal in understanding both fundamental biology and the mechanisms underlying various diseases.

The scientific importance of these cell lines extends to numerous applications in both research and clinical settings. They are invaluable for investigating autoimmune disorders, cancer biology, and therapeutic interventions that target immune system modulation. Furthermore, these models provide insights into drug efficacy and safety, as understanding the impact of gene knockout in cellular responses can guide the development of more effective therapies.

One significant advantage of NDFIP2 Gene Knockout Cell Lines is their specificity; they allow for the examination of gene function without the confounding effects of other signaling pathways, enabling clearer conclusions regarding NDFIP2's roles. Compared to traditional methods such as RNA interference, these knockout models offer more stable and long-lasting gene silencing.

For researchers and clinicians alike, the value of NDFIP2 Gene Knockout Cell Lines lies in their ability to accelerate the understanding of complex biological interactions, leading to advancements in therapeutic development. Our company specializes in high-quality biological products, providing researchers with the tools necessary for groundbreaking scientific discovery and medical advancements. With our expertise and commitment to innovation, we ensure that our products meet the highest standards, enabling researchers to push the frontiers of science effectively.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.