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NCKIPSD Knockout Cell Lines

Gene: NCKIPSD

Official Full Name: NCK interacting protein with SH3 domainprovided by HGNC

Gene Summary: The protein encoded by this gene contains a nuclear localization signal. It plays a role in signal transduction, and may function in the maintenance of sarcomeres and in the assembly of myofibrils into sarcomeres. It also plays an important role in stress fiber formation This protein is involved in the formation and maintenance of dendritic spines, and modulates synaptic activity in neurons. The gene is involved in therapy-related leukemia by a chromosomal translocation t(3;11)(p21;q23) that involves this gene and the myeloid/lymphoid leukemia gene. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Aug 2019]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO22429 NCKIPSD Knockout cell line (HeLa) Human NCKIPSD 1:3~1:6 Negative Online Inquiry
KO22430 NCKIPSD Knockout cell line (HCT 116) Human NCKIPSD 1:2~1:4 Negative Online Inquiry
KO22431 NCKIPSD Knockout cell line (HEK293) Human NCKIPSD 1:3~1:6 Negative Online Inquiry
KO22432 NCKIPSD Knockout cell line (A549) Human NCKIPSD 1:3~1:4 Negative Online Inquiry

Background

NCKIPSD Gene Knockout Cell Lines represent a cutting-edge tool in the realm of genetic research and biomedicine, specifically designed to facilitate comprehensive studies of gene function and regulation. These cell lines have been meticulously engineered through CRISPR-Cas9 technology to excise the NCKIPSD gene, which is implicated in various cellular processes, including cytoskeletal organization and cell signaling pathways. The knockout of this gene provides researchers with a unique model system to dissect its role in cellular dynamics and its potential implications in disease states, such as cancer and neurodegeneration.

The primary function of NCKIPSD gene knockout is the elucidation of loss-of-function phenotypes, enabling researchers to observe the resultant changes in cell behavior, morphology, and signaling. By removing the influence of the NCKIPSD gene, these cell lines allow for the detailed examination of compensatory pathways and networks involved in cellular decision-making processes. This genetic disruption can serve as a powerful tool for understanding the molecular underpinnings of various pathologies and for identifying novel therapeutic targets.

Scientifically, the importance of NCKIPSD gene knockout cell lines extends to their numerous applications in both basic and translational research settings. They serve as invaluable assets in the fields of cancer biology, neurobiology, and developmental biology. The ability to derive insights into gene function helps drive advancements in personalized medicine and the development of new therapeutic strategies.

The advantages and unique selling points of NCKIPSD gene knockout cell lines lie in their specificity, reproducibility, and adaptability. Unlike previous models that may provide incomplete or ambiguous data due to partial gene function, these cell lines ensure complete gene disruption and consistent experimental results. Moreover, they can be readily utilized across a variety of cellular contexts and assay systems, making them highly versatile for different research demands.

For researchers and clinicians seeking to advance their understanding of gene function and associated diseases, NCKIPSD gene knockout cell lines are an indispensable resource. The ability to explore the repercussions of gene inactivation on cellular pathways positions these products at the forefront of genetic research, empowering scientists to uncover new biological insights.

Our company prides itself on delivering high-quality biological products supported by robust scientific expertise and a commitment to advancing research. We ensure that our cell lines maintain the highest standards of quality, reproducibility, and customer satisfaction, enabling our users to make significant contributions to scientific knowledge and innovation.

Please note that all services are for research use only. Not intended for any clinical use.

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