Gene: NAP1L5
Official Full Name: nucleosome assembly protein 1 like 5provided by HGNC
Gene Summary: This gene encodes a protein that shares sequence similarity to nucleosome assembly factors, but may be localized to the cytoplasm rather than the nucleus. Expression of this gene is downregulated in hepatocellular carcinomas. This gene is located within a differentially methylated region (DMR) and is imprinted and paternally expressed. There is a related pseudogene on chromosome 4. [provided by RefSeq, Nov 2015]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO15875 | NAP1L5 Knockout cell line (HeLa) | Human | NAP1L5 | 1:3~1:6 | Negative | Online Inquiry |
KO15876 | NAP1L5 Knockout cell line (HCT 116) | Human | NAP1L5 | 1:2~1:4 | Negative | Online Inquiry |
KO15877 | NAP1L5 Knockout cell line (A549) | Human | NAP1L5 | 1:3~1:4 | Negative | Online Inquiry |
NAP1L5 Gene Knockout Cell Lines represent a powerful tool in the realm of genetic research and therapeutic development. These cell lines are specifically engineered to disable the NAP1L5 gene, which encodes a nuclear protein involved in fundamental cellular processes including chromatin remodeling and gene expression regulation. By utilizing CRISPR-Cas9 technology, these knockout cell lines allow researchers to elucidate the functional significance of NAP1L5 within various biological contexts.
The key function of NAP1L5 Gene Knockout Cell Lines lies in their ability to facilitate the study of gene function and interaction in a controlled environment. By completely abolishing the expression of the NAP1L5 gene, these cell lines enable scientists to investigate the downstream effects of its deletion, such as alterations in chromatin structure, gene transcription, and cellular response to stimuli. This information is critical for understanding the gene’s role in cellular differentiation, proliferation, and potential links to diseases like cancer.
The scientific importance of NAP1L5 Gene Knockout Cell Lines is underscored by their applications in both basic research and clinical settings. They serve as a platform for pharmacological assays, biomarker discovery, and validation of gene-related pathways, which can lead to novel therapeutic targets. In the field of oncology, investigating the role of NAP1L5 could provide insights into tumorigenesis and treatment resistance, enhancing our understanding of cancer biology.
What sets our NAP1L5 Gene Knockout Cell Lines apart from alternatives on the market is our commitment to quality and precision. Each cell line undergoes rigorous validation to ensure the complete knockout of the target gene and characterize the resulting phenotypes. Furthermore, the ease of use and reproducibility of our lines provide convenience that accelerates research timelines. Researchers can focus more on their investigations and less on troubleshooting genetic variability.
In a landscape where precision medicine and targeted therapies are becoming predominant, the value of NAP1L5 Gene Knockout Cell Lines cannot be overstated. They empower researchers and clinicians with the tools they need to explore gene function deeply, paving the way for innovative advancements in treatment strategies and therapeutic interventions.
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