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NACC2 Knockout Cell Lines

Gene: NACC2

Official Full Name: NACC family member 2provided by HGNC

Gene Summary: Enables several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; histone deacetylase binding activity; and protein homodimerization activity. Involved in several processes, including negative regulation of transcription by RNA polymerase II; positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage; and protein homooligomerization. Located in chromatin; mitochondrion; and nucleolus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO26334 NACC2 Knockout cell line (HeLa) Human NACC2 1:3~1:6 Negative Online Inquiry
KO26335 NACC2 Knockout cell line (HCT 116) Human NACC2 1:2~1:4 Negative Online Inquiry
KO26336 NACC2 Knockout cell line (HEK293) Human NACC2 1:3~1:6 Negative Online Inquiry
KO26337 NACC2 Knockout cell line (A549) Human NACC2 1:3~1:4 Negative Online Inquiry

Background

NACC2 Gene Knockout Cell Lines represent a sophisticated tool in molecular biology, specifically designed for the effective study of the NACC2 gene's functional role in cellular mechanisms. These cell lines are meticulously engineered to have the NACC2 gene completely disrupted, providing a valuable opportunity to dissect the implications of gene loss in various biological pathways and disease models.

The functionality of these knockout cell lines lies in their ability to exhibit the phenotypic changes associated with the absence of NACC2 expression, permitting researchers to explore the gene’s involvement in processes such as cellular differentiation, metabolism, and stress response. Mechanistically, the deletion of NACC2 leads to alterations in cellular signaling cascades, which can be monitored through various assays and analyses. This empowers scientists to unravel the gene's contributions to both normal physiology and pathological conditions.

The scientific importance of NACC2 Gene Knockout Cell Lines extends to research in neurodegenerative diseases, obesity, and metabolic disorders, where the NACC2 gene has been implicated. In clinical settings, these cell lines serve as significant models for drug discovery and testing, enabling the identification of therapeutic targets.

What sets our NACC2 Gene Knockout Cell Lines apart from alternatives on the market is their high specificity and reliability, confirmed through rigorous validation processes. Our product provides a more homogeneous and reproducible model compared to traditional methods, such as transient knockdowns, which may yield variable results.

By utilizing NACC2 Gene Knockout Cell Lines, researchers and clinicians can gain crucial insights, drive innovations in therapeutic strategies, and advance personalized medicine approaches. With our expertise in producing high-quality biological tools, our company is dedicated to supporting scientific progress through products that facilitate profound biological discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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