Gene: NAA60
Official Full Name: N-alpha-acetyltransferase 60, NatF catalytic subunitprovided by HGNC
Gene Summary: This gene encodes an enzyme that localizes to the Golgi apparatus, where it transfers an acetyl group to the N-terminus of free proteins. This enzyme acts on histones, and its activity is important for chromatin assembly and chromosome integrity. Alternative splicing and the use of alternative promoters results in multiple transcript variants. The upstream promoter is located in a differentially methylated region (DMR) and undergoes imprinting; transcript variants originating from this position are expressed from the maternal allele. [provided by RefSeq, Nov 2015]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO15914 | NAA60 Knockout cell line (HeLa) | Human | NAA60 | 1:3~1:6 | Negative | Online Inquiry |
KO15915 | NAA60 Knockout cell line (HCT 116) | Human | NAA60 | 1:2~1:4 | Negative | Online Inquiry |
KO15916 | NAA60 Knockout cell line (HEK293) | Human | NAA60 | 1:3~1:6 | Negative | Online Inquiry |
KO15917 | NAA60 Knockout cell line (A549) | Human | NAA60 | 1:3~1:4 | Negative | Online Inquiry |
NAA60 Gene Knockout Cell Lines represent an innovative tool in the realm of molecular biology and genetic research, designed specifically to facilitate the study of NAA60, a gene implicated in various cellular processes including protein acetylation and gene regulation. By utilizing CRISPR/Cas9 technology, these cell lines are genetically modified to disrupt the expression of NAA60, allowing researchers to explore the gene's function and its role in pathophysiological conditions.
The key function of NAA60 Gene Knockout Cell Lines is to provide a robust platform for investigating the consequences of NAA60 absence on cellular behavior and gene expression. Researchers can utilize these cell lines to conduct functional assays, gene expression analyses, and protein interaction studies, thereby elucidating the underlying molecular mechanisms of conditions related to NAA60 dysregulation, such as certain cancers or metabolic disorders. The precise editing capabilities of the CRISPR system ensure that the knockout is specific, reproducible, and versatile across various experimental paradigms.
From a scientific perspective, these cell lines are crucial for advancing our understanding of NAA60 and its broader implications in biological research and clinical applications. They can serve as valuable models for drug discovery and testing, providing insights into potential therapeutic targets. Furthermore, their adaptability makes them suitable for high-throughput screening of small molecules or genetic modifiers, enhancing efficiency during research.
A uniquely advantageous feature of NAA60 Gene Knockout Cell Lines is their consistency and reliability compared to traditional knockout methods. They are easy to use, can be rapidly generated, and yield reproducible results across experiments, unlike older techniques which often suffer from variable expression levels or off-target effects.
For researchers and clinicians alike, the value of NAA60 Gene Knockout Cell Lines is paramount. By enabling the dissection of complex biological pathways and accelerating the pace of discovery, these cell lines open up new avenues for scientific inquiry and clinical innovation. Our company prides itself on its commitment to providing high-quality biological products that are backed by leading-edge technologies and industry expertise, ensuring our customers have the best tools at their disposal for impactful research.
Please note that all services are for research use only. Not intended for any clinical use.
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