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MYO5C Knockout Cell Lines

Gene: MYO5C

Official Full Name: myosin VCprovided by HGNC

Gene Summary: Predicted to enable actin filament binding activity and microfilament motor activity. Predicted to be involved in actin filament organization and vesicle transport along actin filament. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO15943 MYO5C Knockout cell line (HeLa) Human MYO5C 1:3~1:6 Negative Online Inquiry
KO15944 MYO5C Knockout cell line (HCT 116) Human MYO5C 1:2~1:4 Negative Online Inquiry
KO15945 MYO5C Knockout cell line (HEK293) Human MYO5C 1:3~1:6 Negative Online Inquiry
KO15946 MYO5C Knockout cell line (A549) Human MYO5C 1:3~1:4 Negative Online Inquiry

Background

MYO5C Gene Knockout Cell Lines are genetically engineered cell lines that have been specifically modified to disrupt the MYO5C gene, which encodes the protein Myosin 5C. This protein is integral for intracellular transport and cellular signaling, particularly involving the movement of organelles and vesicles along actin filaments. By knocking out the MYO5C gene, researchers can precisely investigate the role of this myosin in various physiological processes and disease states.

The key mechanism of these knockout cell lines involves the use of CRISPR-Cas9 technology, which facilitates targeted gene editing, leading to a complete or partial loss of function of the MYO5C gene. This allows for the detailed study of phenotypic changes resulting from the absence of Myosin 5C, enabling researchers to elucidate its contribution to cellular dynamics, such as endocytosis, exocytosis, and cell motility.

The scientific importance of MYO5C Gene Knockout Cell Lines lies in their applications both in basic research and in clinical studies. They serve as valuable models for understanding diseases linked to cellular transport mechanisms, including neurodegenerative diseases and cancer, where MYO5C may play a critical role. Additionally, these cell lines can aid in drug discovery by providing a platform to test potential therapies aimed at modulating this pathway.

Compared to traditional methods of gene disruption, our MYO5C Gene Knockout Cell Lines offer unparalleled precision, reproducibility, and ease of use, streamlining the experimental workflow for researchers. The immediate availability of these knockout models accelerates the pace of discovery, providing scientists with an essential tool to advance their studies.

Choosing our MYO5C Gene Knockout Cell Lines demonstrates a commitment to high-quality research resources that empower insights into fundamental biological questions. Our company is dedicated to providing cutting-edge genetic tools backed by expertise in molecular biology, ensuring that our products meet the rigorous standards demanded by modern research. With these cell lines, researchers can obtain reliable data and contribute significantly to the scientific community's understanding of intracellular transport mechanisms.

Please note that all services are for research use only. Not intended for any clinical use.

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