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MYO1C Knockout Cell Lines

Gene: MYO1C

Official Full Name: myosin ICprovided by HGNC

Gene Summary: This gene encodes a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of this protein also functions in intracellular vesicle transport to the plasma membrane. Multiple transcript variants encoding different isoforms have been found for this gene. The related gene myosin IE has been referred to as myosin IC in the literature, but it is a distinct locus on chromosome 19. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO36511 MYO1C Knockout cell line (HeLa) Human MYO1C 1:3~1:6 Negative Online Inquiry
KO36512 MYO1C Knockout cell line (HCT 116) Human MYO1C 1:2~1:4 Negative Online Inquiry
KO36513 MYO1C Knockout cell line (HEK293) Human MYO1C 1:3~1:6 Negative Online Inquiry
KO36514 MYO1C Knockout cell line (A549) Human MYO1C 1:3~1:4 Negative Online Inquiry

Background

MYO1C Gene Knockout Cell Lines are genetically engineered cells specifically modified to lack the expression of the MYO1C gene, which encodes for a motor protein involved in various intracellular transport processes. By creating cells that exhibit a non-functional version of this gene, researchers can investigate the gene's role in cellular mechanisms, including motility, cell signaling, and intracellular trafficking. The knockout model facilitates the elucidation of MYO1C's contributions to physiological and pathological states, allowing for a deeper understanding of its potential impact on diseases such as cancer and neurodegeneration.

Key functions of MYO1C include its involvement in clathrin-mediated endocytosis and cytoskeletal organization, which play critical roles in maintaining cellular integrity and function. By disrupting MYO1C expression, researchers can examine the downstream effects of altered cellular dynamics and assess compensatory mechanisms that may arise from its absence. This innovative approach enables the exploration of complex biological systems and pathways that are often difficult to study using traditional methods.

These knockout cell lines hold significant importance in both research and clinical applications. In research settings, they provide a powerful tool for studying the gene's contributions to various cellular processes, impacting fields such as cancer research, neuroscience, and cell biology. Clinically, understanding MYO1C's role may lead to novel therapeutic strategies targeting diseases associated with its dysfunction.

Compared to alternative models, MYO1C Gene Knockout Cell Lines offer unique advantages, including precise gene editing that eliminates off-target effects and allows for consistent replicability in experimental settings. This precision is essential for producing robust and interpretable results, ultimately accelerating the pace of scientific discovery.

The value of our MYO1C Gene Knockout Cell Lines to researchers and clinicians alike lies in their ability to provide clarity in complex biological research while offering insights that could pave the way for breakthroughs in therapeutic interventions. Our company is dedicated to advancing the field of genetic engineering and providing high-quality biological tools tailored to enhance experimental outcomes and drive innovative research.

Please note that all services are for research use only. Not intended for any clinical use.

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