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MYL6B Knockout Cell Lines

Gene: MYL6B

Official Full Name: myosin light chain 6Bprovided by HGNC

Gene Summary: Myosin is a hexameric ATPase cellular motor protein. It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene encodes a myosin alkali light chain expressed in both slow-twitch skeletal muscle and in nonmuscle tissue. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO25617 MYL6B Knockout cell line (HeLa) Human MYL6B 1:3~1:6 Negative Online Inquiry
KO25618 MYL6B Knockout cell line (HCT 116) Human MYL6B 1:2~1:4 Negative Online Inquiry
KO25619 MYL6B Knockout cell line (HEK293) Human MYL6B 1:3~1:6 Negative Online Inquiry
KO25620 MYL6B Knockout cell line (A549) Human MYL6B 1:3~1:4 Negative Online Inquiry

Background

MYL6B Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to eliminate the expression of the MYL6B gene, a critical component involved in muscle contraction and cytoskeletal organization. By utilizing CRISPR-Cas9 technology, these knockout cell lines provide an efficient and targeted approach to studying the biological functions of MYL6B and its implications in various physiological and pathological processes.

The primary function of MYL6B is its role in modulating the actin-myosin interaction during muscle contractions, thus influencing cellular motility and structure. By knocking out this gene, researchers can investigate its contributions to muscle development, hypertrophy, and disorders like cardiac and skeletal muscle diseases. The mechanism operates on the principle of gene editing, allowing scientists to create a model that accurately mimics relevant biological conditions, thereby facilitating deeper insights into the functional genomics of muscle-specific proteins.

The scientific importance of MYL6B Gene Knockout Cell Lines extends to diverse applications in both research and clinical settings. Researchers can use these models to dissect the signaling pathways involved in muscular diseases, screen for potential drug compounds, or study cellular responses to mechanical stress. In a clinical context, understanding MYL6B’s role could advance the development of targeted therapies aimed at muscle degeneration.

Compared to traditional cell lines, MYL6B Gene Knockout Cell Lines offer significant advantages, including a higher specificity in gene editing and reduced off-target effects. This ensures that any observed phenotypes can be attributed directly to the loss of MYL6B function, leading to more robust and reproducible research findings. Additionally, these cell lines provide a unique platform for studying gene function in real-time, an invaluable tool for accelerating biomedical research.

For researchers and clinicians invested in muscle biology and related fields, the MYL6B Gene Knockout Cell Lines present a powerful approach to unravel complex molecular mechanisms and drive innovation in therapeutic interventions. Our company specializes in providing high-quality, rigorously validated biological products that empower scientific discovery. With expertise in genetic engineering and a commitment to advancing research, we are dedicated to equipping the scientific community with the tools necessary to succeed.

Please note that all services are for research use only. Not intended for any clinical use.

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