Gene: MVP
Official Full Name: major vault proteinprovided by HGNC
Gene Summary: This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO06673 | MVP Knockout cell line (HeLa) | Human | MVP | 1:3~1:6 | Negative | Online Inquiry |
KO06674 | MVP Knockout cell line (HCT 116) | Human | MVP | 1:2~1:4 | Negative | Online Inquiry |
KO06675 | MVP Knockout cell line (HEK293) | Human | MVP | 1:3~1:6 | Negative | Online Inquiry |
KO06676 | MVP Knockout cell line (A549) | Human | MVP | 1:3~1:4 | Negative | Online Inquiry |
MVP Gene Knockout Cell Lines represent a crucial innovation in molecular biology, specifically designed for the functional analysis of gene expression and discovery of genetic interactions. These cell lines are genetically modified to facilitate precise gene knockouts, allowing researchers to investigate the role of specific genes in various biological processes. The creation of these knockout lines involves the application of advanced genomic editing techniques, such as CRISPR/Cas9, ensuring targeted and efficient gene disruption.
The primary function of MVP Gene Knockout Cell Lines lies in their ability to elucidate gene function by allowing the observation of phenotypic changes following gene ablation. This provides invaluable insight into gene regulation, pathway analysis, and disease modeling. By systematically disabling genes in a controlled environment, researchers can assess the biological consequences of gene loss, thus advancing our understanding of essential cellular mechanisms.
In both research and clinical settings, these cell lines are indispensable for drug development, genetic studies, and functional assays. They enable scientists to model diseases accurately, leading to the identification of potential therapeutic targets and biomarkers. MVP Gene Knockout Cell Lines hold significant relevance in areas such as cancer research, neurobiology, and developmental biology, where understanding gene functions and interactions is paramount.
Compared to traditional methods of gene knockout, such as homologous recombination, MVP Gene Knockout Cell Lines offer a more efficient, reliable, and time-saving approach. Their rapid generation and the robustness of the knockout process result in higher reproducibility and lower off-target effects, making them a preferred choice for researchers aiming for accuracy in their experimental outcomes.
For researchers, clinicians, and industry professionals, MVP Gene Knockout Cell Lines are a transformative tool that accelerates discovery and innovation, driving advancements in genetic research and therapeutic developments. Our company brings years of expertise in developing high-quality biological products, and we remain committed to empowering the scientific community with reliable tools that support groundbreaking research.
Please note that all services are for research use only. Not intended for any clinical use.
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