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MUC3B Knockout Cell Lines

Gene: MUC3B

Official Full Name: mucin 3B, cell surface associatedprovided by HGNC

Gene Summary: Predicted to be located in Golgi lumen and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO20395 MUC3B Knockout cell line (HeLa) Human MUC3B 1:3~1:6 Negative Online Inquiry
KO20396 MUC3B Knockout cell line (HCT 116) Human MUC3B 1:2~1:4 Negative Online Inquiry
KO20397 MUC3B Knockout cell line (HEK293) Human MUC3B 1:3~1:6 Negative Online Inquiry
KO20398 MUC3B Knockout cell line (A549) Human MUC3B 1:3~1:4 Negative Online Inquiry

Background

MUC3B Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to lack the expression of the MUC3B gene, which is known to play a significant role in mucin production and cellular signaling pathways. By utilizing CRISPR/Cas9 or other gene-editing technologies, these cell lines serve as vital tools for studying the biological functions of the MUC3B gene, its implications in various physiological processes, and its potential involvement in diseases, particularly in cancer biology and inflammatory conditions.

The primary function of these knockout cell lines is to facilitate research into the role of MUC3B in cellular mechanisms such as cell adhesion, immune response modulation, and tumorigenesis. By analyzing the differing phenotypes and signaling alterations that occur in the absence of MUC3B, researchers gain insights into the gene's effects on cellular behavior and its influence on disease progression. This has important implications for the development of targeted therapies, as understanding these mechanisms can help identify potential therapeutic targets.

Scientifically, MUC3B Gene Knockout Cell Lines have become invaluable in both research and clinical settings. They allow for the dissection of fundamental biological processes and the examination of pathological states, making them critical for researchers focusing on translational medicine. These cell lines also pave the way for studies on drug responses, enabling researchers to scrutinize how the loss of MUC3B affects treatment efficacy.

One of the distinct advantages of using MUC3B Gene Knockout Cell Lines over other models is their specificity and precision in gene targeting. Conventional cell lines may express varying levels of MUC3B, leading to inconsistent results. In contrast, our knockout lines provide a uniform model that eliminates confounding variables, thereby enhancing experimental reproducibility. Moreover, our proprietary protocols ensure high viability and functionality of the knockout cell lines, making them reliable choices for diverse applications.

Researchers and clinicians seeking cutting-edge tools for gene function analysis and therapeutic explorations will find tremendous value in MUC3B Gene Knockout Cell Lines. The ability to pinpoint the functional consequences of gene loss elevates the potential to innovate within the realm of personalized medicine and targeted therapies.

With our dedication to advancing scientific research and a track record of developing high-quality biological products, our expertise positions us as a trusted partner in the quest for understanding complex biological systems and improving clinical outcomes.

Please note that all services are for research use only. Not intended for any clinical use.

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