Gene: MTX1
Official Full Name: metaxin 1provided by HGNC
Gene Summary: Predicted to be involved in mitochondrion organization. Located in mitochondrion. Part of SAM complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO04343 | MTX1 Knockout cell line (HeLa) | Human | MTX1 | 1:3~1:6 | Negative | Online Inquiry |
KO04344 | MTX1 Knockout cell line (HCT 116) | Human | MTX1 | 1:2~1:4 | Negative | Online Inquiry |
KO04345 | MTX1 Knockout cell line (HEK293) | Human | MTX1 | 1:3~1:6 | Negative | Online Inquiry |
KO04346 | MTX1 Knockout cell line (A549) | Human | MTX1 | 1:3~1:4 | Negative | Online Inquiry |
MTX1 Gene Knockout Cell Lines are a pivotal tool for researchers studying gene function and regulation in cellular processes. These cell lines are engineered to have a complete knockout of the MTX1 gene, which is associated with various biochemical pathways, including those involved in cellular metabolism and proliferation. By eliminating the MTX1 gene, researchers can dissect its specific contributions to cellular behavior, thereby enabling a deeper understanding of its role in health and disease.
The core mechanism of action involves CRISPR-Cas9 technology, where specific guide RNAs direct the Cas9 nuclease to the MTX1 loci, resulting in targeted DNA cleavage and subsequent gene disruption. This precise editing allows for the observation of phenotypic changes and alterations in signaling pathways, making these cell lines invaluable for functional genomics studies.
Scientifically, MTX1 Gene Knockout Cell Lines are crucial for applications ranging from cancer research to metabolic disorder investigations. They provide insights into how the absence of MTX1 influences cell survival, differentiation, and response to therapeutic agents, making them indispensable for both academic laboratories and clinical research settings.
Compared to alternative models, MTX1 knockout cell lines offer several unique advantages, including reproducibility, stability, and a well-characterized genome edit that enhances research reliability. Their ability to model specific genetic deficiencies in vitro presents a clearer picture of disease mechanisms compared to other, less defined systems.
For researchers and clinicians seeking to unravel complex biological questions, the MTX1 Gene Knockout Cell Lines are a valuable addition to their toolkit. Our company prides itself on its extensive expertise in genetic engineering and cell line development, ensuring the highest quality and reliability in our product offerings, thus empowering the scientific community to advance their research with confidence.
Please note that all services are for research use only. Not intended for any clinical use.
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