Gene: MTERF3
Official Full Name: mitochondrial transcription termination factor 3provided by HGNC
Gene Summary: Enables transcription cis-regulatory region binding activity. Involved in negative regulation of DNA-templated transcription. Located in cytosol and mitochondrial matrix. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23215 | MTERF3 Knockout cell line (HeLa) | Human | MTERF3 | 1:3~1:6 | Negative | Online Inquiry |
KO23216 | MTERF3 Knockout cell line (HCT 116) | Human | MTERF3 | 1:2~1:4 | Negative | Online Inquiry |
KO23217 | MTERF3 Knockout cell line (HEK293) | Human | MTERF3 | 1:3~1:6 | Negative | Online Inquiry |
KO23218 | MTERF3 Knockout cell line (A549) | Human | MTERF3 | 1:3~1:4 | Negative | Online Inquiry |
MTERF3 Gene Knockout Cell Lines are specialized cellular models designed to study the function of the MTERF3 gene, which plays a critical role in mitochondrial gene expression and biogenesis. These cell lines are meticulously engineered using CRISPR-Cas9 technology to enable precise disruption of the MTERF3 gene, providing researchers with invaluable tools for investigating the gene's biological pathways and its influence on mitochondrial dynamics.
The primary function of MTERF3 involves the regulation of mitochondrial transcription and translation, impacting oxidative phosphorylation and energy metabolism. By utilizing MTERF3 Gene Knockout Cell Lines, scientists can elucidate the downstream effects of MTERF3 deficiency, including alterations in mitochondrial function, reactive oxygen species production, and potential development of metabolic disorders. These models are particularly pertinent in research focused on conditions such as neurodegenerative diseases, metabolic syndromes, and cancer, where mitochondrial dysfunction is often a hallmark.
One of the unique advantages of MTERF3 Gene Knockout Cell Lines is their specificity; they allow for the targeted dissection of MTERF3-related pathways without the interference of other genetic factors. This level of precision can yield more reliable data when assessing the impacts of mitochondrial irregularities, making these cell lines superior to traditional models that may introduce confounding variables.
Moreover, MTERF3 Gene Knockout Cell Lines provide researchers and clinicians with a streamlined approach to study mitochondrial biology, supporting high-throughput screening applications, drug discovery efforts, and the development of therapeutic strategies. Their ability to mimic pathophysiological conditions in vitro significantly contributes to the understanding of disease mechanisms and potential interventions.
As a company at the forefront of genetic and cellular engineering, our expertise in creating and providing high-quality biological models ensures that researchers have access to reliable, innovative products that enhance their scientific inquiries. With MTERF3 Gene Knockout Cell Lines, we empower your research endeavors with unparalleled insights into mitochondrial function and health.
Please note that all services are for research use only. Not intended for any clinical use.
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