Gene: MST1R
Official Full Name: macrophage stimulating 1 receptorprovided by HGNC
Gene Summary: This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta subunits, generated by proteolytic cleavage of a single-chain precursor. The beta subunit undergoes tyrosine phosphorylation upon stimulation by MSP. This protein is expressed on the ciliated epithelia of the mucociliary transport apparatus of the lung, and together with MSP, thought to be involved in host defense. Alternative splicing generates multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Jan 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO08048 | MST1R Knockout cell line (HeLa) | Human | MST1R | 1:3~1:6 | Negative | Online Inquiry |
KO08049 | MST1R Knockout cell line (HCT 116) | Human | MST1R | 1:2~1:4 | Negative | Online Inquiry |
KO08050 | MST1R Knockout cell line (HEK293) | Human | MST1R | 1:3~1:6 | Negative | Online Inquiry |
KO08051 | MST1R Knockout cell line (A549) | Human | MST1R | 1:3~1:4 | Negative | Online Inquiry |
MST1R Gene Knockout Cell Lines are specifically engineered cellular models that lack the expression of the Macrophage Stimulating 1 Receptor (MST1R). These knockout cell lines serve as a critical tool for researchers studying the physiological and pathological roles of MST1R in immune response, inflammation, and cancer biology. The ablation of this receptor allows for comprehensive investigations into its downstream signaling pathways, cellular interactions, and potential therapeutic targets.
The key functions of MST1R involve its role in cell survival, migration, and modulation of innate immune responses. Through the action of its ligands, MST1R activates various signaling cascades that influence macrophage function and tumor microenvironment dynamics. By utilizing these knockout cell lines, researchers can isolate the effects of MST1R signaling, allowing for clearer understanding of its biological implications and the development of innovative therapeutic strategies.
Scientifically, MST1R Gene Knockout Cell Lines hold significant importance for both basic and applied research. They find applications in cancer studies, immunology, and drug development, providing a platform for screening potential therapeutic agents or investigating immune evasion mechanisms in tumors. The insight gained from these cell lines can translate into advancements in clinical settings, including the design of MST1R-targeted therapies.
Compared to traditional models, these knockout cell lines offer distinct advantages. They enable real-time observation of the absence of MST1R signaling in a controlled environment, reducing confounding variables inherent in other experimental setups. Additionally, these models are reproducible and can be engineered into various cellular backgrounds, increasing their versatility for diverse research applications.
For researchers and clinicians focused on deciphering complex biological processes, MST1R Gene Knockout Cell Lines represent an invaluable resource that drives innovation and accelerates discovery. With a commitment to excellence in biological products, our company stands at the forefront of providing high-quality, reliable cell lines that enhance research outcomes and pave the way for future breakthroughs.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.