Gene: MORC4
Official Full Name: MORC family CW-type zinc finger 4provided by HGNC
Gene Summary: In human, the four current members of the microrchidia (morc) gene family share an N-terminal ATPase-like ATP-binding region and a CW four-cysteine zinc-finger motif. The protein encoded by this gene also has a nuclear matrix binding domain and a two-stranded coiled-coil motif near its C-terminus. This gene is widely expressed at low levels in normal tissues and has elevated expression in placenta and testis. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jan 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO16110 | MORC4 Knockout cell line (HeLa) | Human | MORC4 | 1:3~1:6 | Negative | Online Inquiry |
KO16111 | MORC4 Knockout cell line (HCT 116) | Human | MORC4 | 1:2~1:4 | Negative | Online Inquiry |
KO16112 | MORC4 Knockout cell line (HEK293) | Human | MORC4 | 1:3~1:6 | Negative | Online Inquiry |
KO16113 | MORC4 Knockout cell line (A549) | Human | MORC4 | 1:3~1:4 | Negative | Online Inquiry |
MORC4 Gene Knockout Cell Lines are specialized cell culture models engineered to lack the MORC4 gene, a critical player in various cellular processes, including chromatin remodeling and gene regulation. These knockout lines enable researchers to study the functional consequences of MORC4 deletion, elucidating its role in essential biological pathways and disease mechanisms. By offering a precise and defined genetic alteration, these cell lines serve as powerful tools for dissecting the pathways involved in cancer, neurodegeneration, and other pathologies linked to MORC4 dysregulation.
The key function of MORC4 Gene Knockout Cell Lines lies in their ability to mimic the loss of function of the MORC4 gene, providing insights into the corresponding phenotypic changes. Researchers can observe alterations in cell proliferation, apoptosis, and gene expression patterns, enabling them to understand the gene's role in cellular homeostasis. Furthermore, these knockout models facilitate the identification of downstream signaling cascades and potential therapeutic targets, accelerating the translation of laboratory findings into clinical applications.
The scientific importance of these cell lines cannot be overstated. They offer unique advantages, such as reproducibility and precision in experimental setups, which are critical for translational research. Compared to traditional overexpression models or chemical inhibitor approaches, MORC4 Gene Knockout Cell Lines provide unambiguous insights into the gene's function. This specificity is especially valuable in drug development, as it allows researchers to validate the potential of targeting MORC4 in therapeutic regimens with high confidence.
Given the increasing emphasis on personalized medicine, our MORC4 Gene Knockout Cell Lines offer significant advantages to researchers and clinicians seeking to understand the genetic landscapes of various diseases. By employing these advanced models, users can better tailor their research and clinical strategies, leading to more effective patient outcomes.
As a company committed to advancing biological research, we bring extensive expertise in the development of high-quality genetic models. Our dedication ensures that our MORC4 Gene Knockout Cell Lines are rigorously validated and optimized for a range of applications, equipping researchers with the tools necessary to push the boundaries of scientific discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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