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MOB3B Knockout Cell Lines

Gene: MOB3B

Official Full Name: MOB kinase activator 3Bprovided by HGNC

Gene Summary: The protein encoded by this gene shares similarity with the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation. This gene is located on the opposite strand as the interferon kappa precursor (IFNK) gene. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO16122 MOB3B Knockout cell line (HeLa) Human MOB3B 1:3~1:6 Negative Online Inquiry
KO16123 MOB3B Knockout cell line (HCT 116) Human MOB3B 1:2~1:4 Negative Online Inquiry
KO16124 MOB3B Knockout cell line (HEK293) Human MOB3B 1:3~1:6 Negative Online Inquiry
KO16125 MOB3B Knockout cell line (A549) Human MOB3B 1:3~1:4 Negative Online Inquiry

Background

MOB3B Gene Knockout Cell Lines are advanced cellular models engineered to specifically disrupt the MOB3B gene, which plays a pivotal role in various cellular processes, including cell cycle regulation and signal transduction pathways. This product utilizes CRISPR-Cas9 gene-editing technology to achieve precise modifications in the genomic DNA of mammalian cell lines, creating a versatile platform for studying the functional implications of MOB3B deficiency in a range of biological contexts.

The primary function of these cell lines is to facilitate the investigation of the physiological and pathological roles of the MOB3B gene. By creating knockout models, researchers can elucidate the effects of gene ablation on cellular behaviors, such as proliferation, apoptosis, and response to growth factors. The intrinsic mechanism of action relies on the CRISPR-Cas9 system, which introduces double-strand breaks at specific loci, leading to insertion or deletion mutations that fully disable gene activity.

Scientifically, MOB3B Gene Knockout Cell Lines hold great importance in both research and clinical settings. They enable investigators to study disease models, particularly in cancer research, where dysregulation of cellular signaling pathways is prevalent. Moreover, these cell lines are invaluable for screening potential therapeutics, providing insights into gene function that could pave the way for innovative treatment strategies.

What sets our MOB3B Gene Knockout Cell Lines apart from alternatives is the assurance of high specificity and efficiency of gene editing, along with extensive characterization of the cell lines to validate knockout efficiency. This reduces the burden of off-target effects and enhances reproducibility and reliability in experimental outcomes.

For researchers and clinicians aiming to unravel complex biological mechanisms and develop targeted interventions, the MOB3B Gene Knockout Cell Lines present a crucial tool that addresses critical gaps in current methodologies. Our commitment to scientific innovation is underscored by our extensive expertise in cell line development, ensuring that every product is backed by rigorous testing and quality assurance to meet the highest standards of research excellence.

Please note that all services are for research use only. Not intended for any clinical use.

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