Gene: MMP28
Official Full Name: matrix metallopeptidase 28provided by HGNC
Gene Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix for both normal physiological processes, such as embryonic development, reproduction and tissue remodeling, and disease processes, such as asthma and metastasis. This gene encodes a secreted enzyme that degrades casein. Its expression pattern suggests that it plays a role in tissue homeostasis and in wound repair. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO16136 | MMP28 Knockout cell line (HeLa) | Human | MMP28 | 1:3~1:6 | Negative | Online Inquiry |
KO16137 | MMP28 Knockout cell line (HEK293) | Human | MMP28 | 1:3~1:6 | Negative | Online Inquiry |
KO16138 | MMP28 Knockout cell line (A549) | Human | MMP28 | 1:3~1:4 | Negative | Online Inquiry |
MMP28 Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the matrix metalloproteinase 28 (MMP28) gene, a member of the MMP family known for its role in the degradation of extracellular matrix components. By creating knockout variants, researchers can investigate the functional implications of MMP28's absence on cell behavior, tissue remodeling, and disease progression. These cell lines serve as crucial tools for elucidating the precise biological functions of MMP28, including its potential involvement in wound healing, inflammation, and tumor metastasis.
The mechanism of action regarding MMP28 involves the breakdown of extracellular matrix proteins, influencing various cellular processes such as migration, proliferation, and apoptosis. Knockout of MMP28 enables scientists to delineate its specific contributions to these processes, offering insights into how its dysregulation may lead to pathological states. The MMP28 Gene Knockout Cell Lines are particularly valuable in research that seeks to understand the roles of MMPs in cancer biology and tissue repair, as they can provide a controlled environment to study alterations in cellular activities that relate to MMP28 function.
In comparison to alternative models, the MMP28 Gene Knockout Cell Lines offer unique advantages, such as enhanced specificity and the ability to monitor cellular responses devoid of MMP28's influence. This specificity allows for clearer interpretation of experimental results, facilitating more robust scientific conclusions. Researchers and clinicians can benefit from this product as it provides a means to more accurately dissect the contributions of MMP28 in health and disease, paving the way for potential therapeutic targets or biomarkers in clinical settings.
As a company with a strong commitment to advancing biological research, we specialize in developing high-quality genetic models, including MMP28 Gene Knockout Cell Lines. Our expertise ensures that each product meets rigorous standards, empowering researchers and clinicians to deepen their understanding and drive the next generation of breakthroughs in regenerative medicine and oncology.
Please note that all services are for research use only. Not intended for any clinical use.
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