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MINAR1 Knockout Cell Lines

Gene: MINAR1

Official Full Name: membrane integral NOTCH2 associated receptor 1provided by HGNC

Gene Summary: Involved in several processes, including negative regulation of TOR signaling; negative regulation of angiogenesis; and negative regulation of protein ubiquitination. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO29607 MINAR1 Knockout cell line (HeLa) Human MINAR1 1:3~1:6 Negative Online Inquiry
KO29608 MINAR1 Knockout cell line (HCT 116) Human MINAR1 1:2~1:4 Negative Online Inquiry
KO29609 MINAR1 Knockout cell line (HEK293) Human MINAR1 1:3~1:6 Negative Online Inquiry
KO29610 MINAR1 Knockout cell line (A549) Human MINAR1 1:3~1:4 Negative Online Inquiry

Background

MINAR1 Gene Knockout Cell Lines are specifically engineered cellular models that enable precise study of gene function and regulation associated with the MINAR1 gene. These cell lines have been developed using advanced CRISPR-Cas9 technology, allowing for targeted editing that renders the MINAR1 gene non-functional. The mechanism underlying the functionality of these knockout cell lines hinges on the introduction of specific guide RNAs that direct the Cas9 nuclease to the MINAR1 gene locus, resulting in a double-strand break which is subsequently repaired by non-homologous end joining, leading to insertions or deletions that disrupt gene coding sequences.

The scientific significance of MINAR1 Gene Knockout Cell Lines is underscored by their wide-ranging applications in biomedical research. They serve as invaluable tools for elucidating the biological pathways associated with MINAR1 and understanding its role in health and disease, particularly in contexts such as cancer research and genetic susceptibility studies. By allowing researchers to observe the phenotypic consequences of MINAR1 loss, these cell lines can provide insights into cancer progression, therapeutic resistance, and potential molecular targets for drug development.

What sets our MINAR1 Gene Knockout Cell Lines apart from traditional models is their high efficiency, specificity, and reproducibility. Unlike earlier gene knockout strategies which were often time-consuming and less reliable, our CRISPR-engineered cell lines promise a streamlined approach, ensuring consistent results across experiments. Additionally, they are compatible with high-throughput screening methods, enhancing productivity and accelerating research timelines.

For researchers and clinicians focused on genetic studies and their implications for disease mechanisms, MINAR1 Gene Knockout Cell Lines offer a unique value proposition that is crucial in advancing their studies. Our commitment to providing high-quality biological products is grounded in years of research and development, placing our company at the forefront of innovation in genetic modeling.

Please note that all services are for research use only. Not intended for any clinical use.

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