Gene: MGA
Official Full Name: MAX dimerization protein MGAprovided by HGNC
Gene Summary: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell fate specification and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within cellular response to leukemia inhibitory factor. Part of MLL1 complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO05899 | MGA Knockout cell line (HeLa) | Human | MGA | 1:3~1:6 | Negative | Online Inquiry |
KO05900 | MGA Knockout cell line (HCT 116) | Human | MGA | 1:2~1:4 | Negative | Online Inquiry |
KO05901 | MGA Knockout cell line (HEK293) | Human | MGA | 1:3~1:6 | Negative | Online Inquiry |
KO05902 | MGA Knockout cell line (A549) | Human | MGA | 1:3~1:4 | Negative | Online Inquiry |
MGA Gene Knockout Cell Lines are genetically engineered cell lines designed specifically to facilitate the study of the MGA (Macrophage Galactose N-Acetylgalactosamine Specific Lectin) gene's function and role in various biological processes. By introducing targeted deletions in the MGA gene, these knockout cell lines allow researchers to elucidate the gene's contribution to cellular processes such as immune response, cell signaling, and oncogenesis. The mechanism relies on CRISPR-Cas9 technology, enabling precise editing of the genomic DNA and ensuring that the resulting cell lines lack functional MGA protein.
The significance of MGA Gene Knockout Cell Lines lies in their broad applications across research and clinical settings. Researchers can investigate the implications of MGA loss in cellular pathways and its effect on the physiological and pathological states of various diseases, including cancers and autoimmune disorders. Additionally, these knockout lines serve as important tools for drug discovery and therapeutic development by providing models to test the efficacy of potential treatments that target biomolecular pathways involving MGA.
One of the key advantages of MGA Gene Knockout Cell Lines compared to traditional knockout models is their rapid generation and high efficiency. The precision inherent in CRISPR-Cas9 editing minimizes off-target effects, ensuring the authenticity of research findings. Moreover, these cell lines can be easily integrated into existing workflows, making them accessible and convenient for a range of applications in biology and medicine.
For researchers and clinicians, the MGA Gene Knockout Cell Lines represent a valuable tool for dissecting complex genetic interactions and exploring novel therapeutic avenues. Their precise engineering and functional insights into the gene's role promise to enhance our understanding of critical biological mechanisms.
Our company is dedicated to the advancement of biological research, offering a portfolio enriched with cutting-edge genetic tools, including the MGA Gene Knockout Cell Lines. Backed by a team of experienced scientists, we ensure that our products meet the highest standards of quality and reliability to empower researchers in their quest for scientific discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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