Gene: MFHAS1
Official Full Name: multifunctional ROCO family signaling regulator 1provided by HGNC
Gene Summary: Identified in a human 8p amplicon, this gene is a potential oncogene whose expression is enhanced in some malignant fibrous histiocytomas (MFH). The primary structure of its product includes an ATP/GTP-binding site, three leucine zipper domains, and a leucine-rich tandem repeat, which are structural or functional elements for interactions among proteins related to the cell cycle, and which suggest that overexpression might be oncogenic with respect to MFH. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO33390 | MFHAS1 Knockout cell line (HeLa) | Human | MFHAS1 | 1:3~1:6 | Negative | Online Inquiry |
KO33391 | MFHAS1 Knockout cell line (HCT 116) | Human | MFHAS1 | 1:2~1:4 | Negative | Online Inquiry |
KO33392 | MFHAS1 Knockout cell line (HEK293) | Human | MFHAS1 | 1:3~1:6 | Negative | Online Inquiry |
KO33393 | MFHAS1 Knockout cell line (A549) | Human | MFHAS1 | 1:3~1:4 | Negative | Online Inquiry |
MFHAS1 Gene Knockout Cell Lines are specially engineered cellular models designed to facilitate the study of the MFHAS1 gene's functional roles and its implications in various biological processes. By using the CRISPR-Cas9 genome-editing technology, these cell lines feature precise alterations in the MFHAS1 gene, allowing researchers to investigate the effects of gene loss-of-function on cellular behavior, signaling pathways, and overall physiology.
The key mechanism underlying these knockout cell lines involves the disruption of the MFHAS1 gene, which is crucial for the synthesis of certain metabolites involved in cellular metabolism and signaling cascades. The absence of MFHAS1 provides researchers with a unique opportunity to explore its contributions to critical processes such as cellular growth, apoptosis, and response to stressors, thereby revealing potential links to various diseases, including cancer and metabolic disorders.
The scientific importance of MFHAS1 Gene Knockout Cell Lines cannot be overstated. In research settings, they serve as invaluable tools to elucidate gene function and regulatory networks, while in clinical research, they can help identify therapeutic targets and biomarkers. Their application extends to drug discovery, as they offer a platform for assessing the efficacy and safety of new pharmacological agents by evaluating their effects in a controlled genetic context.
What sets MFHAS1 Gene Knockout Cell Lines apart from traditional cell models is their precision and specificity, ensuring reliable and reproducible results that are critical for high-quality research. Unlike alternative models, which may feature background genetic variability, these knockout lines provide a uniform context for experiments, enhancing the integrity of the research findings.
For researchers and clinicians, the value of MFHAS1 Gene Knockout Cell Lines lies in their ability to drive significant advancements in understanding gene function and disease mechanisms. They empower users to generate deeper insights into cellular behaviors and possible therapeutic interventions.
Our company, specializing in advanced genetic models and biotechnological innovations, is committed to providing high-quality research tools that empower the scientific community. With a focus on accuracy and reliability, we ensure that our MFHAS1 Gene Knockout Cell Lines meet the highest standards, enabling groundbreaking research and discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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