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MFAP3 Knockout Cell Lines

Gene: MFAP3

Official Full Name: microfibril associated protein 3provided by HGNC

Gene Summary: Predicted to enable MHC class II protein binding activity and protein tyrosine kinase binding activity. Predicted to be involved in T cell activation; interleukin-15-mediated signaling pathway; and positive regulation of ERK1 and ERK2 cascade. Predicted to be located in extracellular region. Predicted to be active in external side of plasma membrane and membrane raft. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO36654 MFAP3 Knockout cell line (HeLa) Human MFAP3 1:3~1:6 Negative Online Inquiry
KO36655 MFAP3 Knockout cell line (HCT 116) Human MFAP3 1:2~1:4 Negative Online Inquiry
KO36656 MFAP3 Knockout cell line (HEK293) Human MFAP3 1:3~1:6 Negative Online Inquiry
KO36657 MFAP3 Knockout cell line (A549) Human MFAP3 1:3~1:4 Negative Online Inquiry

Background

MFAP3 Gene Knockout Cell Lines are genetically engineered cell lines in which the MFAP3 gene has been selectively disrupted, offering researchers valuable tools for investigating the gene's biological functions and its implications in various disease contexts. These knockout cell lines are generated using advanced CRISPR/Cas9 technology, enabling precise alterations in the genome. By targeting and inactivating the MFAP3 gene, these cell lines provide a unique platform to study the role of MFAP3 in cellular processes such as extracellular matrix formation, cell signaling, and tissue regeneration.

The key function of MFAP3 is its involvement in the structural organization of the extracellular matrix, which plays a critical role in tissue integrity and cellular behavior. By using these knockout cell lines, researchers can elucidate the impact of MFAP3 loss on cellular characteristics and pathways, enabling deeper insights into its association with conditions such as cardiovascular diseases, cancer progression, and other pathologies where matrix components are dysregulated.

In research and clinical settings, the MFAP3 Gene Knockout Cell Lines are invaluable for their ability to provide a clear in vivo-like environment to study complex biological processes. Their applications range from basic research aimed at understanding fundamental biological mechanisms to translational research that seeks to identify novel therapeutic targets.

Compared to traditional cell lines that express the MFAP3 gene, these knockout variants offer superior specificity and relevance. They enable more accurate modeling of diseases associated with MFAP3 dysregulation, reduce background noise from non-specific gene expression, and ultimately increase the reliability of experimental outcomes.

For researchers and clinicians focused on the intersection of genetics, cell biology, and disease intervention, MFAP3 Gene Knockout Cell Lines present a significant advantage. They empower users to discover groundbreaking insights and therapeutic strategies in the context of MFAP3-associated conditions.

With extensive experience in developing precision biological products, our company ensures that the MFAP3 Gene Knockout Cell Lines are rigorously validated and optimized for superior performance. Our commitment to scientific excellence and innovation positions us as a trusted partner for researchers striving to advance their understanding in the rapidly evolving field of molecular biology.

Please note that all services are for research use only. Not intended for any clinical use.

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