Home / METTL5 Knockout Cell Lines

METTL5 Knockout Cell Lines

Gene: METTL5

Official Full Name: methyltransferase 5, N6-adenosineprovided by HGNC

Gene Summary: Enables S-adenosyl-L-methionine binding activity and rRNA (adenine-N6-)-methyltransferase activity. Involved in positive regulation of translation and rRNA methylation. Located in several cellular components, including fibrillar center; postsynapse; and presynapse. Implicated in autosomal recessive intellectual developmental disorder 72. [provided by Alliance of Genome Resources, Apr 2025]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
GP00370 METTL5 gRNA1-gRNA2 KO plasmid METTL5 $850
KO03003 METTL5 Knockout cell line (HeLa) Human METTL5 1:3~1:6 Negative Online Inquiry
KO03004 METTL5 Knockout cell line (HCT 116) Human METTL5 1:2~1:4 Negative Online Inquiry
KO03005 METTL5 Knockout cell line (HEK293) Human METTL5 1:3~1:6 Negative Online Inquiry
KO03006 METTL5 Knockout cell line (A549) Human METTL5 1:3~1:4 Negative Online Inquiry

Background

METTL5 Gene Knockout Cell Lines are a sophisticated biological tool designed to facilitate the study of gene function and regulation by specifically targeting the METTL5 gene. METTL5, a member of the methyltransferase family, plays crucial roles in cellular processes such as mRNA methylation and translation regulation. By utilizing CRISPR/Cas9 technology, these knockout cell lines provide researchers with a powerful means to study the effects of METTL5 loss-of-function in various biological contexts, including cancer, neurodegeneration, and immune responses.

The key function of these cell lines lies in their ability to mimic specific genetic deficiencies, allowing for in-depth analysis of the downstream effects on cellular pathways and gene expression profiles. When METTL5 is knocked out, alterations in mRNA modification patterns lead to significant changes in protein synthesis, which can be quantitatively analyzed using next-generation sequencing or proteomic approaches. This mechanistic insight is invaluable for researchers who aim to elucidate the roles of mRNA modifications in health and disease.

In research settings, METTL5 Gene Knockout Cell Lines can be instrumental in drug discovery, biomarker identification, and pathway analysis. They are particularly useful in developing targeted therapies aimed at modifying the translational landscape of cancer cells or other mutated cell types. Clinically, understanding METTL5 functions can lead to novel therapeutic strategies for diseases linked to dysregulation of methylation processes.

What sets METTL5 Gene Knockout Cell Lines apart from competitors is their high specificity and validated performance in a range of assays. Unlike traditional gene knockout methods, which may produce off-target effects, our precisely engineered cell lines ensure that researchers achieve reliable and reproducible results, enhancing the robustness of their findings.

For researchers and clinicians alike, the significance of METTL5 Gene Knockout Cell Lines lies in their ability to bridge the gap between fundamental science and potential clinical applications. They empower users to uncover new insights into gene regulation mechanisms, paving the way for innovative therapeutic approaches.

As a company dedicated to advancing biological research, we pride ourselves on our expertise in cutting-edge gene editing technologies and our commitment to providing high-quality products that meet the evolving needs of the scientific community.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.