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METTL2B Knockout Cell Lines

Gene: METTL2B

Official Full Name: methyltransferase 2B, tRNA N3-cytidineprovided by HGNC

Gene Summary: This gene is a member of a family of methyltransferases that share homology with, but are distinct from, the UbiE family of methyltransferases. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO16236 METTL2B Knockout cell line (HeLa) Human METTL2B 1:3~1:6 Negative Online Inquiry
KO16237 METTL2B Knockout cell line (HCT 116) Human METTL2B 1:2~1:4 Negative Online Inquiry
KO16238 METTL2B Knockout cell line (HEK293) Human METTL2B 1:3~1:6 Negative Online Inquiry
KO16239 METTL2B Knockout cell line (A549) Human METTL2B 1:3~1:4 Negative Online Inquiry

Background

METTL2B Gene Knockout Cell Lines are custom-engineered cellular models designed to facilitate the study of the METTL2B gene, which plays a crucial role in RNA methylation and gene expression regulation. By utilizing CRISPR/Cas9 technology, these cell lines have been genetically modified to effectively knockout the METTL2B gene, providing researchers with a powerful tool to investigate its functional consequences and implications in various biological processes.

The primary mechanism of action involves the disruption of METTL2B gene expression, which subsequently affects RNA modifications and downstream gene regulation. This knockout model helps elucidate the roles of METTL2B in cellular pathways such as proliferation, differentiation, and response to environmental signals. Researchers can observe changes in gene expression profiles, metabolic pathways, and cellular behavior, thereby providing insights that may lead to advancements in understanding complex diseases, including cancer and neurological disorders.

The scientific importance of METTL2B Gene Knockout Cell Lines extends to both research and clinical applications, making them an essential resource for molecular biologists and pharmacologists. In research settings, they can be employed in drug discovery, functional genomics, and disease modeling. Clinically, insights gained from METTL2B knockout studies may contribute to the development of targeted therapies or novel diagnostics.

Compared to traditional gene knockout methods, our METTL2B Gene Knockout Cell Lines offer enhanced precision, specificity, and reproducibility due to the use of state-of-the-art CRISPR technology. Additionally, these cell lines are validated for consistent performance, ensuring reliability in experimental outcomes.

For researchers and clinicians seeking innovative solutions to further their studies and therapeutic strategies, METTL2B Gene Knockout Cell Lines represent a valuable addition to the toolkit. With our expertise in cellular engineering and commitment to advancing scientific research, we provide unparalleled support and resources to help unlock the potential of your investigations.

Please note that all services are for research use only. Not intended for any clinical use.

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