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METTL27 Knockout Cell Lines

Gene: METTL27

Official Full Name: methyltransferase like 27provided by HGNC

Gene Summary: This gene encodes a protein belonging to ubiE/COQ5 methyltransferase family. The gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.22-q11.23. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO16213 METTL27 Knockout cell line (HeLa) Human METTL27 1:3~1:6 Negative Online Inquiry
KO16214 METTL27 Knockout cell line (HCT 116) Human METTL27 1:2~1:4 Negative Online Inquiry
KO16215 METTL27 Knockout cell line (A549) Human METTL27 1:3~1:4 Negative Online Inquiry

Background

METTL27 Gene Knockout Cell Lines are engineered cell lines that have undergone targeted gene editing to completely eliminate the expression of the METTL27 gene. This process allows researchers to gain valuable insights into the gene's function, its role in various biological pathways, and its implications in diseases. By using CRISPR-Cas9 technology, these cell lines enable precise targeting and knockout of the METTL27 gene, facilitating the study of its contribution to cellular processes such as RNA methylation and gene expression regulation.

The primary function of METTL27 is believed to be associated with the regulation of RNA modifications, which play critical roles in gene expression, stability, and translation. By studying METTL27 knockout cell lines, researchers can observe phenotypic changes, potentially linking MOD-27 to oncogenic processes, developmental biology, or neurobiology, depending on the context of the study. The ability to eliminate the expression of this gene allows for the dissection of its biological functions and interactions in cellular networks.

Scientifically, these knockout cell lines are invaluable in both research and clinical applications. They can be utilized in drug discovery, targeting METTL27-related pathways, or for investigating the molecular mechanisms of various diseases, including cancers and neurodegenerative disorders. Moreover, this product aids in validating potential targets for therapeutic interventions, thus accelerating the pace of biomedical research.

In comparison to alternative gene editing strategies, METTL27 Gene Knockout Cell Lines offer a streamlined and robust approach, reducing off-target effects that are often seen in less-specific knockdown methods. By using these cell lines, researchers can achieve more reliable and reproducible results, making them a superior choice for experimental designs.

The value of METTL27 Gene Knockout Cell Lines lies in their versatility and the depth of understanding they provide regarding gene function and disease mechanisms. Researchers and clinicians can rely on these innovative tools to push the boundaries of knowledge and explore groundbreaking treatments with high precision.

Our company specializes in the production of high-quality gene knockout and knock-in models, leveraging cutting-edge techniques and a commitment to scientific advancement. We provide researchers with the tools necessary to unlock potential discoveries and contribute to meaningful scientific progress, ensuring customer satisfaction with every product.

Please note that all services are for research use only. Not intended for any clinical use.

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