Gene: METTL17
Official Full Name: methyltransferase like 17provided by HGNC
Gene Summary: Enables 4 iron, 4 sulfur cluster binding activity. Involved in mitochondrial small ribosomal subunit assembly. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO20729 | METTL17 Knockout cell line (HeLa) | Human | METTL17 | 1:3~1:6 | Negative | Online Inquiry |
KO20730 | METTL17 Knockout cell line (HCT 116) | Human | METTL17 | 1:2~1:4 | Negative | Online Inquiry |
KO20731 | METTL17 Knockout cell line (HEK293) | Human | METTL17 | 1:3~1:6 | Negative | Online Inquiry |
METTL17 Gene Knockout Cell Lines are genetically engineered cellular models designed to study the functional implications of the METTL17 gene, a member of the N6-methyladenosine methyltransferase family. These cell lines feature a complete knockout of the METTL17 gene, allowing researchers to investigate the gene’s role in cellular processes such as RNA methylation, gene expression regulation, and mitochondrial function. The knockout mechanism disrupts normal gene activity and provides a tool to observe physiological changes resulting from the absence of METTL17, facilitating a deeper understanding of its contributions to various metabolic pathways.
The primary functions of these cell lines lie in their utility for exploring the molecular underpinnings of gene regulation and its impact on cellular metabolism and disease. By examining how the loss of METTL17 affects mitochondrial dynamics and overall cell viability, researchers can better elucidate its significance in health and disease states, particularly in cancers and metabolic disorders. The versatile nature of these knockout lines makes them invaluable in both basic research settings and clinical investigations where understanding gene function is pivotal.
Compared to other genetic models, the METTL17 Gene Knockout Cell Lines offer a distinct advantage through their precise knockout design, ensuring a clean background for the study of the METTL17 gene. This specificity reduces potential confounding factors frequently seen in knockdown models, enabling clearer interpretations of cellular responses.
The value of this product lies in its capacity to empower researchers and clinicians with reliable data regarding the METTL17 gene’s impact on various biological processes. The insights gained from studies using these cell lines can lead to the development of novel therapeutic strategies, particularly for conditions linked to mitochondrial dysfunction and aberrant methylation patterns.
Our company specializes in providing high-quality, genetically modified cell lines that support the advancement of scientific research. With expertise in gene editing technologies and a commitment to precision, our METTL17 Gene Knockout Cell Lines stand out as an essential resource for advancing your research initiatives in molecular biology and genetics.
Please note that all services are for research use only. Not intended for any clinical use.
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