Gene: MECR
Official Full Name: mitochondrial trans-2-enoyl-CoA reductaseprovided by HGNC
Gene Summary: The protein encoded by this gene is an oxidoreductase that catalyzes the last step in mitochondrial fatty acid synthesis. Defects in this gene are a cause of childhood-onset dystonia and optic atrophy. [provided by RefSeq, Mar 2017]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23045 | MECR Knockout cell line (HeLa) | Human | MECR | 1:3~1:6 | Negative | Online Inquiry |
KO23046 | MECR Knockout cell line (HCT 116) | Human | MECR | 1:2~1:4 | Negative | Online Inquiry |
KO23047 | MECR Knockout cell line (HEK293) | Human | MECR | 1:3~1:6 | Negative | Online Inquiry |
KO23048 | MECR Knockout cell line (A549) | Human | MECR | 1:3~1:4 | Negative | Online Inquiry |
MECR Gene Knockout Cell Lines are specialized cellular models engineered to selectively disrupt the MECR gene, a critical component involved in mitochondrial fatty acid metabolism. These cell lines provide researchers with a powerful tool to investigate the biological consequences of MECR gene loss and its implications in metabolic disorders, including obesity, diabetes, and cardiovascular diseases. By utilizing CRISPR-Cas9 technology, these knockout cell lines allow for precise genomic editing, resulting in a high degree of specificity and efficiency in the generation of MECR-deficient cells.
The primary function of these cell lines is to facilitate the study of the MECR gene's physiological roles and its interplay with various metabolic pathways. Deletion of the MECR gene has been shown to affect mitochondrial function and lipid homeostasis, leading to potential disruptions in energy metabolism. Researchers can employ these cell lines in various experimental setups to elucidate the gene’s role in disease mechanisms, assess therapeutic targets, and screen for novel pharmacological compounds.
These MECR Gene Knockout Cell Lines hold significant scientific importance in both research and clinical settings, as they enable the exploration of gene function in a controlled environment. The ability to dissect the ramifications of MECR loss on cellular metabolism enhances our understanding of related pathophysiological processes, thereby laying the groundwork for innovative treatment strategies.
One of the distinguishing advantages of our MECR Gene Knockout Cell Lines is their validated and reliable performance compared to other gene disruption models. Additionally, the availability of these knockout models simplifies the research process; they are ready-to-use and save valuable time for scientists who are often pressed to produce results. Furthermore, they offer high reproducibility and consistency across experiments, reducing variability and enhancing data integrity.
For researchers, clinicians, and biotech companies, the MECR Gene Knockout Cell Lines are invaluable tools that provide insights into mitochondrial biology and disease mechanisms. Understanding the role of MECR in metabolic regulation could reveal new avenues for therapeutic intervention and significantly impact public health outcomes.
Our commitment to quality and innovation is reflected in our comprehensive portfolio of genetic tools. With extensive expertise in genetic engineering and cell line development, our company is dedicated to empowering researchers with the resources they need to push the boundaries of science and unlock new discoveries in cellular metabolism and beyond.
Please note that all services are for research use only. Not intended for any clinical use.
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